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1.14.18.9: 4alpha-methylsterol monooxygenase

This is an abbreviated version!
For detailed information about 4alpha-methylsterol monooxygenase, go to the full flat file.

Word Map on EC 1.14.18.9

Reaction

3beta-hydroxy-4beta-methyl-5alpha-cholest-7-ene-4alpha-carbaldehyde
+ 2 ferrocytochrome b5 +
O2
+ 2 H+ =
3beta-hydroxy-4beta-methyl-5alpha-cholest-7-ene-4alpha-carboxylate
+ 2 ferricytochrome b5 +
H2O

Synonyms

4,4-dimethyl-sterol 4alpha-methyl-oxidase, 4,4-dimethyl-zymosterol 4alpha-methyl-oxidase, 4-methyl sterol oxidase, 4-methylsterol oxidase, C-4 methyl sterol oxidase, C-4 sterol methyl oxidase, EC 1.14.13.72, EC 1.14.99.16, ERG25, ERG25p, GintSMO protein, methyl sterol oxidase, methylsterol hydroxylase, methylsterol monooxygenase, NAD(P)H-dependent methylsterol oxidase, SC4MOL, SMO, sterol C-4 methyloxidase, sterol C4 methyl oxidase, sterol-C4-methyl oxidase, sterol-C4-methyl-oxidase

ECTree

     1 Oxidoreductases
         1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
             1.14.18 With another compound as one donor, and incorporation of one atom of oxygen into the other donor
                1.14.18.9 4alpha-methylsterol monooxygenase

Localization

Localization on EC 1.14.18.9 - 4alpha-methylsterol monooxygenase

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LOCALIZATION
ORGANISM
UNIPROT
COMMENTARY hide
GeneOntology No.
LITERATURE
SOURCE
-
the enzyme forms a demethylation complex in the ER together with the transmembrane protein Erg28p, and possibly the other C-4 demethylation proteins Erg26p, overview
Manually annotated by BRENDA team
additional information
-
subcellular localization study
-
Manually annotated by BRENDA team