1.14.18.9: 4alpha-methylsterol monooxygenase

This is an abbreviated version!
For detailed information about 4alpha-methylsterol monooxygenase, go to the full flat file.

Reaction

Synonyms

4,4-dimethyl-sterol 4alpha-methyl-oxidase, 4,4-dimethyl-zymosterol 4alpha-methyl-oxidase, 4-methyl sterol oxidase, 4-methylsterol oxidase, C-4 methyl sterol oxidase, C-4 sterol methyl oxidase, EC 1.14.13.72, EC 1.14.99.16, ERG25, ERG25p, GintSMO protein, methyl sterol oxidase, methylsterol hydroxylase, methylsterol monooxygenase, NAD(P)H-dependent methylsterol oxidase, SC4MOL, SMO, sterol C-4 methyloxidase, sterol C4 methyl oxidase, sterol-C4-methyl oxidase, sterol-C4-methyl-oxidase

ECTree

     1 Oxidoreductases

         1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen

             1.14.18 With another compound as one donor, and incorporation of one atom of oxygen into the other donor

                1.14.18.9 4alpha-methylsterol monooxygenase

Advanced search results

Do not include text mining results

Include results (more...)

Include results (more...)

Results	in table
112	AA Sequence
2	Application
1	CAS Registry Number
4	Cloned(Commentary)
10	Cofactor
62	Disease/ Diagnostics
4	General Information
8	Inhibitors
1	Ki Value [mM]
2	KM Value [mM]
18	Localization
1	Metals/Ions
3	Molecular Weight [Da]
15	Natural Substrates/ Products (Substrates)
182	Organism
9	Pathway
2	pI Value
3	Posttranslational Modification
7	Protein Variants
4	Purification (Commentary)
7	Reaction
3	Reaction Type
19	Reference
12	Source Tissue
6	Specific Activity [micromol/min/mg]
1	Storage Stability
28	Substrates and Products (Substrate)
8	Subunits
37	Synonyms
1	Systematic Name

General Information

print visible entries

print all entries

General Information on EC 1.14.18.9 - 4alpha-methylsterol monooxygenase

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.

top print hide show all columns Go to General Information Search

Please wait a moment until the data is sorted. This message will disappear when the data is sorted.

GENERAL INFORMATION

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

malfunction

2 entries

metabolism

Rhizophagus intraradices

C5HVZ4

first of three steps to remove 2 C4 methyl groups from an intermediate in ergosterol biosynthesis in the sterol biosynthetic pathway, an enzymatic complex is formed with other enzymes in the pathway

698075

physiological function

Homo sapiens

-

the enzyme regulates epidermal growth factor receptor signaling and vesicular trafficking

727093

malfunction

Homo sapiens

-

deficiency of sterol C4 methyl oxidase, is associated with microcephaly, congenital cataracts, and growth delay in infancy

727093

malfunction

Homo sapiens

Q15800

mutations in methyl sterol oxidase cause psoriasiform dermatitis, arthralgias, congenital cataracts, microcephaly, and developmental delay. Enzyme deficiency also substantially alters immunocyte phenotype and in vitro function

728037