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1.14.20.6: flavonol synthase

This is an abbreviated version!
For detailed information about flavonol synthase, go to the full flat file.

Word Map on EC 1.14.20.6

Reaction

a dihydroflavonol
+
2-oxoglutarate
+
O2
=
a flavonol
+
succinate
+
CO2
+
H2O

Synonyms

AaFLS1, BnFLS, Cs-COR054, Cs-COR113, EC 1.14.11.23, FKS2, flavonoid 2-oxoglutarate-dependent dioxygenase, flavonol synthase, FLS, FLS1, FLS2, fls3, McFLS, NtFLS1, PhFLS, PpFLS, RrFLS1, SbFLS, VcFLS

ECTree

     1 Oxidoreductases
         1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
             1.14.20 With 2-oxoglutarate as one donor, and the other dehydrogenated
                1.14.20.6 flavonol synthase

Inhibitors

Inhibitors on EC 1.14.20.6 - flavonol synthase

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INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
2,2'-dipyridyl
-
2 mM, 90% inhibition
3-hydroxy-5-oxo-4-butyryl-cyclohex-3-ene-1-carboxylic acid ethyl ester
3-hydroxy-5-oxo-4-cyclopropanecarbonyl-cyclohex-3-ene-1-carboxylic acid ethyl ester
3-hydroxy-5-oxo-4-propionyl-cyclohex-3-ene-1-(2-dimethylamino)-thiazole
3-hydroxy-5-oxo-4-propionyl-cyclohex-3-ene-1-carbaldehyde
3-hydroxy-5-oxo-4-propionyl-cyclohex-3-ene-1-carbothioic acid S-ethyl ester
3-hydroxy-5-oxo-4-propionyl-cyclohex-3-ene-1-pentanoic acid
benzene-1,2,4,5-tetracarboxylic acid
calcium 3-hydroxy-5-oxo-4-propionyl-cyclohex-3-ene-1-carboxylate
diethyldicarbonate
-
2 mM, 16% inhibition
diethyldithiocarbamate
-
2 mM, 80% inhibition
EDTA
-
5 mM, 94% inhibition
KCN
-
5 mM, 63% inhibition
p-hydroxymercuribenzoate
-
0.1 mM, 89% inhibition
pyrazole-3,5-dicarboxylic acid
pyridine-2,4-dicarboxylic acid diethyl ester
pyridine-2,5-dicarboxylic acid
pyridine-3,4-dicarboxylic acid
sodium 4,6-dioxo-2,2-dimethyl-5-(1-alloxyamino-butylidene)-cyclohexane-1-carboxylic acid methyl ester