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1.14.18.11: plant 4alpha-monomethylsterol monooxygenase

This is an abbreviated version!
For detailed information about plant 4alpha-monomethylsterol monooxygenase, go to the full flat file.

Reaction

24-methylidenelophenol
+ 2 ferrocytochrome b5 +
O2
 + 2 H+ =
4alpha-(hydroxymethyl)ergosta-7,24(241)-dien-3beta-ol
 + 2 ferricytochrome b5 +
H2O

Synonyms

4alpha-methyl oxidase, 4alpha-methyl-DELTA7-sterol-4alpha-methyl-oxidase, 4alpha-methylsterol C4 oxidase, 4alpha-methylsterol-4alpha-methyl-oxidase, 4alpha-MSO, methylsterol monooxygenase 2, SMO2, SMO2-1, SMO2-2, sterol-4alpha-methyl oxidase 2

ECTree

     1 Oxidoreductases
         1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
             1.14.18 With another compound as one donor, and incorporation of one atom of oxygen into the other donor
                1.14.18.11 plant 4alpha-monomethylsterol monooxygenase

Reference

topprint

Reference on EC 1.14.18.11 - plant 4alpha-monomethylsterol monooxygenase

Please use the Reference Search for a specific query.
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REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Darnet, S.; Rahier, A.
Plant sterol biosynthesis: identification of two distinct families of sterol 4alpha-methyl oxidases
Biochem. J.
378
889-898
2004
Nicotiana benthamiana (Q5J954), Nicotiana tabacum (Q6YAU6), Arabidopsis thaliana (Q8VWZ8), Arabidopsis thaliana (Q9ZW22)
Manually annotated by BRENDA team
Rahier, A.; Smith, M.; Taton, M.
The role of cytochrome b5, in 4alpha-methyl-oxidation and C5(6) desaturation of plant sterol precursors
Biochem. Biophys. Res. Commun.
236
434-437
1997
Zea mays
Manually annotated by BRENDA team
Darnet, S.; Bard, M.; Rahier, A.
Functional identification of sterol-4alpha-methyl oxidase cDNAs from Arabidopsis thaliana by complementation of a yeast erg25 mutant lacking sterol-4alpha-methyl oxidation
FEBS Lett.
508
39-43
2001
Arabidopsis thaliana (Q9ZW22)
Manually annotated by BRENDA team
Zhang, J.; Li, X.; Lu, F.; Wang, S.; An, Y.; Su, X.; Li, X.; Ma, L.; Han, G.
De novo sequencing and transcriptome analysis reveal key genes regulating steroid metabolism in leaves, roots, adventitious roots and calli of Periploca sepium Bunge
Front. Plant Sci.
8
594
2017
Periploca sepium
Manually annotated by BRENDA team
Pascal, S.; Taton, M.; Rahier, A.
Plant sterol biosynthesis. Identification and characterization of two distinct microsomal oxidative enzymatic systems involved in sterol C4-demethylation
J. Biol. Chem.
268
11639-11654
1993
Zea mays
Manually annotated by BRENDA team
Ramadan, A.; Azeiz, A.; Baabad, S.; Hassanein, S.; Gadalla, N.; Hassan, S.; Algandaby, M.; Bakr, S.; Khan, T.; Abouseadaa, H.; Ali, H.; Al-Ghamdi, A.; Osman, G.; Edris, S.; Eissa, H.; Bahieldin, A.
Control of beta-sitosterol biosynthesis under light and watering in desert plant Calotropis procera
Steroids
141
1-8
2019
Calotropis procera
Manually annotated by BRENDA team
Rahier, A.
Dissecting the sterol C-4 demethylation process in higher plants. From structures and genes to catalytic mechanism
Steroids
76
340-352
2011
Arabidopsis thaliana
Manually annotated by BRENDA team