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1.14.14.92: benzoate 4-monooxygenase

This is an abbreviated version!
For detailed information about benzoate 4-monooxygenase, go to the full flat file.

Word Map on EC 1.14.14.92

Reaction

benzoate
+
[reduced NADPH-hemoprotein reductase]
 +
O2
=
4-hydroxybenzoate
 +
[oxidized NADPH-hemoprotein reductase]
 +
H2O

Synonyms

An09g03500, benzoate 1,2-dioxygenase, benzoate 4-hydroxylase, benzoate para-hydroxylase, benzoate-4-hydroxylase, benzoate-p-hydroxylase, benzoic 4-hydroxylase, benzoic acid 4-hydroxylase, BphA, Cyp1, CYP53A15, CYP53B1, EC 1.14.13.12, hydroxylase, benzoate 4-, More, oxygenase, benzoate 4-mono-

ECTree

     1 Oxidoreductases
         1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
             1.14.14 With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
                1.14.14.92 benzoate 4-monooxygenase

Substrates Products

Substrates Products on EC 1.14.14.92 - benzoate 4-monooxygenase

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SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
2-chlorobenzoate + [reduced NADPH-hemoprotein reductase] + O2
2-chloro-4-hydroxybenzoate + [oxidized NADPH-hemoprotein reductase] + H2O
show the reaction diagram
-
-
-
?
2-fluorobenzoate + [reduced NADPH-hemoprotein reductase] + O2
2-fluoro-4-hydroxybenzoate + [oxidized NADPH-hemoprotein reductase] + H2O
show the reaction diagram
-
-
-
?
2-hydroxybenzoate + [reduced NADPH-hemoprotein reductase] + O2
2,4-dihydroxybenzoate + [oxidized NADPH-hemoprotein reductase] + H2O
show the reaction diagram
-
-
-
?
2-methylbenzoate + [reduced NADPH-hemoprotein reductase] + O2
2-methyl-4-hydroxybenzoate + [oxidized NADPH-hemoprotein reductase] + H2O
show the reaction diagram
-
-
-
?
2-methylbenzoic acid + NADPH + O2
4-hydroxy-2-methylbenzoic acid + NADP+ + H2O
show the reaction diagram
-
-
-
?
3-chlorobenzoate + [reduced NADPH-hemoprotein reductase] + O2
3-chloro-4-hydroxybenzoate + [oxidized NADPH-hemoprotein reductase] + H2O
show the reaction diagram
-
-
-
?
3-fluorobenzoate + [reduced NADPH-hemoprotein reductase] + O2
3-fluoro-4-hydroxybenzoate + [oxidized NADPH-hemoprotein reductase] + H2O
show the reaction diagram
-
-
-
?
3-hydroxybenzoate + [reduced NADPH-hemoprotein reductase] + O2
3,4-dihydroxybenzoate + [oxidized NADPH-hemoprotein reductase] + H2O
show the reaction diagram
-
-
-
?
3-hydroxybenzoic acid + [reduced NADPH-hemoprotein reductase] + O2
3,4-dihydroxybenzoic acid + [oxidized NADPH-hemoprotein reductase] + H2O
show the reaction diagram
reaction of 3-hydroxybenzoate 4-monooxygenase, EC 1.14.13.23
-
-
?
3-methoxybenzoate + [reduced NADPH-hemoprotein reductase] + O2
3-methoxy-4-hydroxybenzoate + [oxidized NADPH-hemoprotein reductase] + H2O
show the reaction diagram
-
-
-
?
3-methylbenzoate + [reduced NADPH-hemoprotein reductase] + O2
3-methyl-4-hydroxybenzoate + [oxidized NADPH-hemoprotein reductase] + H2O
show the reaction diagram
-
-
-
?
3-methylbenzoic acid + [reduced NADPH-hemoprotein reductase] + O2
4-hydroxy-3-methylbenzoic acid + [oxidized NADPH-hemoprotein reductase] + H2O
show the reaction diagram
-
-
-
?
4-chlorobenzoate + [reduced NADPH-hemoprotein reductase] + O2
?
show the reaction diagram
-
-
-
-
?
4-methylbenzoate + [reduced NADPH-hemoprotein reductase] + O2
?
show the reaction diagram
-
-
-
-
?
benzoate + 6,7-dimethyltetrahydropterin + O2
4-hydroxybenzoate + oxidized 6,7-dimethyltetrahydropterin + H2O
show the reaction diagram
-
-
-
-
r
benzoate + NADH + H+ + O2
4-hydroxybenzoate + NAD+ + H2O
show the reaction diagram
-
-
-
-
r
benzoate + NADPH + H+ + O2
4-hydroxybenzoate + NADP+ + H2O
show the reaction diagram
benzoate + [reduced NADPH-hemoprotein reductase] + O2
2-hydro-1,2-dihydroxybenzoate + [oxidized NADPH-hemoprotein reductase] + H2O
show the reaction diagram
benzoate + [reduced NADPH-hemoprotein reductase] + O2
4-hydroxybenzoate + [oxidized NADPH-hemoprotein reductase] + H2O
show the reaction diagram
benzoic acid + [reduced NADPH-hemoprotein reductase] + O2
4-hydroxybenzoic acid + [oxidized NADPH-hemoprotein reductase] + H2O
show the reaction diagram
cinnamate + [reduced NADPH-hemoprotein reductase] + O2
4-coumarate + [oxidized NADPH-hemoprotein reductase] + H2O
show the reaction diagram
-
very low turnover rate
-
?
nicotinate + [reduced NADPH-hemoprotein reductase] + O2
?
show the reaction diagram
-
-
-
-
?
picolinate + [reduced NADPH-hemoprotein reductase] + O2
?
show the reaction diagram
-
-
-
-
?