1.14.14.92: benzoate 4-monooxygenase

This is an abbreviated version!
For detailed information about benzoate 4-monooxygenase, go to the full flat file.

Reaction

Synonyms

An09g03500, benzoate 1,2-dioxygenase, benzoate 4-hydroxylase, benzoate para-hydroxylase, benzoate-4-hydroxylase, benzoate-p-hydroxylase, benzoic 4-hydroxylase, benzoic acid 4-hydroxylase, BphA, Cyp1, CYP53A15, CYP53B1, EC 1.14.13.12, hydroxylase, benzoate 4-, More, oxygenase, benzoate 4-mono-

ECTree

     1 Oxidoreductases

         1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen

             1.14.14 With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor

                1.14.14.92 benzoate 4-monooxygenase

Advanced search results

Do not include text mining results

Include results (more...)

Include results (more...)

Results	in table
5	Activating Compound
38	AA Sequence
2	Application
1	CAS Registry Number
6	Cloned(Commentary)
5	Cofactor
1	Crystallization (Commentary)
1	Expression
2	General Information
5	General Stability
43	Inhibitors
3	Ki Value [mM]
16	KM Value [mM]
3	Localization
4	Metals/Ions
2	Molecular Weight [Da]
6	Natural Substrates/ Products (Substrates)
25	Organism
4	Pathway
4	pH Optimum
2	pH Range
1	pH Stability
4	Purification (Commentary)
1	Reaction
3	Reaction Type
22	Reference
3	Source Tissue
5	Specific Activity [micromol/min/mg]
3	Storage Stability
38	Substrates and Products (Substrate)
1	Subunits
20	Synonyms
1	Systematic Name
3	Temperature Optimum [°C]
1	Temperature Range [°C]
17	Turnover Number [1/s]

Application

print visible entries

print all entries

Application on EC 1.14.14.92 - benzoate 4-monooxygenase

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.

top print hide show all columns Go to Application Search

Please wait a moment until the data is sorted. This message will disappear when the data is sorted.

APPLICATION

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

medicine

Curvularia lunata

B8QM33

the enzyme is involved in detoxification of benzoate, a key intermediate in aromatic compound metabolism in fungi. Because this enzyme is unique to fungi, it is a promising drug target in fungal pathogens of other eukaryotes

742764

pharmacology

Curvularia lunata

B8QM33

the enzyme is involved in detoxification of benzoate, a key intermediate in aromatic compound metabolism in fungi. Because this enzyme is unique to fungi, it is a promising drug target in fungal pathogens of other eukaryotes. By identifying selected derivatives of cinnamic acid as possible antifungal drugs, and CYP53 family enzymes as their targets, a potential inhibitor-target system for antifungal drugs is developed

742764