Reference on EC 2.3.1.291 - sphingoid base N-palmitoyltransferase
Please use the Reference Search for a specific query.
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
REF. 
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Tosetti, B.; Brodesser, S.; Brunn, A.; Deckert, M.; Blueher, M.; Doehner, W.; Anker, S.D.; Wenzel, D.; Fleischmann, B.; Pongratz, C.; Peters, F.; Utermoehlen, O.; Kroenke, M.
A tissue-specific screen of ceramide expression in aged mice identifies ceramide synthase-1 and ceramide synthase-5 as potential regulators of fiber size and strength in skeletal muscle
Aging Cell
19
e13049
2019
Homo sapiens (Q8N5B7), Mus musculus (Q9D6K9)
Mizutani, Y.; Kihara, A.; Igarashi, Y.
Mammalian Lass6 and its related family members regulate synthesis of specific ceramides
Biochem. J.
390
263-271
2005
Mus musculus (Q9D6K9)
Wegner, M.S.; Wanger, R.A.; Oertel, S.; Brachtendorf, S.; Hartmann, D.; Schiffmann, S.; Marschalek, R.; Schreiber, Y.; Ferreiros, N.; Geisslinger, G.; Groesch, S.
Ceramide synthases CerS4 and CerS5 are upregulated by 17beta-estradiol and GPER1 via AP-1 in human breast cancer cells
Biochem. Pharmacol.
92
577-589
2014
Homo sapiens (Q8N5B7), Homo sapiens (Q9HA82)
Brachtendorf, S.; Wanger, R.A.; Birod, K.; Thomas, D.; Trautmann, S.; Wegner, M.S.; Fuhrmann, D.C.; Bruene, B.; Geisslinger, G.; Groesch, S.
Chemosensitivity of human colon cancer cells is influenced by a p53-dependent enhancement of ceramide synthase 5 and induction of autophagy
Biochim. Biophys. Acta
1863
1214-1227
2018
Homo sapiens (Q8N5B7)
Mesicek, J.; Lee, H.; Feldman, T.; Jiang, X.; Skobeleva, A.; Berdyshev, E.V.; Haimovitz-Friedman, A.; Fuks, Z.; Kolesnick, R.
Ceramide synthases 2, 5, and 6 confer distinct roles in radiation-induced apoptosis in HeLa cells
Cell. Signal.
22
1300-1307
2010
Homo sapiens (Q8N5B7)
Jiang, Z.; Li, F.; Wan, Y.; Han, Z.; Yuan, W.; Cao, L.; Deng, Y.; Peng, X.; Chen, F.; Fan, X.; Liu, X.; Dai, G.; Wang, Y.; Zeng, Q.; Shi, Y.; Zhou, Z.; Chen, Y.; Xu, W.; Luo, S.; Chen, S.; Ye, X.; Mo, X.; Wu, X.; Li, Y.
LASS5 interacts with SDHB and synergistically represses p53 and p21 activity
Curr. Mol. Med.
16
582-590
2016
Homo sapiens (Q8N5B7)
Frangioudakis, G.; Diakanastasis, B.; Liao, B.Q.; Saville, J.T.; Hoffman, N.J.; Mitchell, T.W.; Schmitz-Peiffer, C.
Ceramide accumulation in L6 skeletal muscle cells due to increased activity of ceramide synthase isoforms has opposing effects on insulin action to those caused by palmitate treatment
Diabetologia
56
2697-701
2013
Homo sapiens (Q8N5B7)
Mojakgomo, R.; Mbita, Z.; Dlamini, Z.
Linking the ceramide synthases (CerSs) 4 and 5 with apoptosis, endometrial and colon cancers
Exp. Mol. Pathol.
98
585-592
2015
Homo sapiens (Q8N5B7), Homo sapiens (Q9HA82)
Choi, S.; Snider, J.M.; Olakkengil, N.; Lambert, J.M.; Anderson, A.K.; Ross-Evans, J.S.; Cowart, L.A.; Snider, A.J.
Myristate-induced endoplasmic reticulum stress requires ceramide synthases 5/6 and generation of C14-ceramide in intestinal epithelial cells
FASEB J.
32
5724-5736
2018
Mus musculus (Q9D6K9)
Becker, I.; Wang-Eckhardt, L.; Yaghootfam, A.; Gieselmann, V.; Eckhardt, M.
Differential expression of (dihydro)ceramide synthases in mouse brain oligodendrocyte-specific expression of CerS2/Lass2
Histochem. Cell Biol.
129
233-241
2008
Mus musculus (Q9D6K9)
Lahiri, S.; Futerman, A.H.
LASS5 is a bona fide dihydroceramide synthase that selectively utilizes palmitoyl-CoA as acyl donor
J. Biol. Chem.
280
33735-33738
2005
Mus musculus (Q9D6K9)
Laviad, E.L.; Kelly, S.; Merrill, A.H.; Futerman, A.H.
Modulation of ceramide synthase activity via dimerization
J. Biol. Chem.
287
21025-21033
2012
Homo sapiens (Q8N5B7)
Gosejacob, D.; Jaeger, P.S.; Vom Dorp, K.; Frejno, M.; Carstensen, A.C.; Koehnke, M.; Degen, J.; Doermann, P.; Hoch, M.
Ceramide synthase 5 is essential to maintain C16 0-ceramide pools and contributes to the development of diet-induced obesity
J. Biol. Chem.
291
6989-7003
2016
Mus musculus (Q9D6K9)
Sassa, T.; Hirayama, T.; Kihara, A.
Enzyme activities of the ceramide synthases CERS2-6 are regulated by phosphorylation in the C-terminal region
J. Biol. Chem.
291
7477-7487
2016
Homo sapiens (Q8N5B7), Mus musculus (Q9D6K9)
Xu, Z.; Zhou, J.; McCoy, D.M.; Mallampalli, R.K.
LASS5 is the predominant ceramide synthase isoform involved in de novo sphingolipid synthesis in lung epithelia
J. Lipid Res.
46
1229-1238
2005
Mus musculus (Q9D6K9)
Garic, D.; De Sanctis, J.B.; Wojewodka, G.; Houle, D.; Cupri, S.; Abu-Arish, A.; Hanrahan, J.W.; Hajduch, M.; Matouk, E.; Radzioch, D.
Fenretinide differentially modulates the levels of long- and very long-chain ceramides by downregulating Cers5 enzyme evidence from bench to bedside
J. Mol. Med.
95
1053-1064
2017
Homo sapiens (Q8N5B7), Mus musculus (Q9D6K9)
html completed
