Cloned (Comment) | Organism |
---|---|
overexpression in L6 myotubes | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | Q8N5B7 | - |
- |
General Information | Comment | Organism |
---|---|---|
physiological function | overexpression of isoform Cers5 leads to accumulation of C16:0 ceramides. Presence of insulin has no effect on sphingomyelins, while palmitate treatment causes a significant decrease in several species, including the predominant C16:0 species. CerS5 knockdown reduces glycogen synthesis in the absence or presence of palmitate. Isoform CerS1 overexpression results in minor upregulation of endogenous CerS5 | Homo sapiens |