2.3.1.293: meromycolic acid 3-oxoacyl-(acyl carrier protein) synthase I
This is an abbreviated version!
For detailed information about meromycolic acid 3-oxoacyl-(acyl carrier protein) synthase I, go to the full flat file.
Word Map on EC 2.3.1.293
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2.3.1.293
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polyketide
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cerulenin
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malonyl
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isoniazid
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6-deoxyerythronolide
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condensing
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mycolic
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diketide
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malonyl-acp
- 2.3.1.293
- polyketide
- cerulenin
-
malonyl
- isoniazid
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6-deoxyerythronolide
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condensing
-
mycolic
-
diketide
- malonyl-acp
Reaction
Synonyms
beta-ketoacyl ACP synthase, beta-ketoacyl ACP synthase I, beta-ketoacyl acyl carrier protein synthase, beta-ketoacyl-ACP synthase, beta-ketoacyl-AcpM synthase, beta-ketoacyl-AcpM synthase A, beta-ketoacyl-acyl carrier protein synthase, beta-ketoacyl-acyl carrier protein synthase KasA, beta-ketoacyl-acyl-carrier protein synthase, beta-ketoacylacyl synthase, KasA, Rv2245
ECTree
2.3.1.293 meromycolic acid 3-oxoacyl-(acyl carrier protein) synthase IAdvanced search results
results (
results (KI Value
KI Value on EC 2.3.1.293 - meromycolic acid 3-oxoacyl-(acyl carrier protein) synthase I
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Ki VALUE [mM] 
INHIBITOR
ORGANISM
UNIPROT
COMMENTARY 
LITERATURE
IMAGE
0.0082
(5R)-3-acetyl-4-hydroxy-5-methyl-5-[(1E)-2-methylbuta-1,3-dien-1-yl]thiophen-2(5H)-one
-
pH and temperature not specified in the publication
0.0652
(5R)-3-butanoyl-4-hydroxy-5-methyl-5-[(1E)-2-methylbuta-1,3-dien-1-yl]thiophen-2(5H)-one
-
pH and temperature not specified in the publication
0.357
(5R)-3-ethyl-4-hydroxy-5-methyl-5-[(1E)-2-methylbuta-1,3-dien-1-yl]thiophen-2(5H)-one
-
pH and temperature not specified in the publication
0.105
(5R)-3-hexadecanoyl-4-hydroxy-5-methyl-5-[(1E)-2-methylbuta-1,3-dien-1-yl]thiophen-2(5H)-one
-
pH and temperature not specified in the publication
0.4
(5R)-3-[2-(4-chlorophenyl)ethyl]-4-hydroxy-5-methyl-5-[(1E)-2-methylbuta-1,3-dien-1-yl]thiophen-2(5H)-one
-
pH and temperature not specified in the publication
0.0774
(5R)-3-[4-(4-chlorophenyl)butyl]-4-hydroxy-5-methyl-5-[(1E)-2-methylbuta-1,3-dien-1-yl]thiophen-2(5H)-one
-
pH and temperature not specified in the publication
0.069
(5R)-3-[4-(4-fluorophenyl)butyl]-4-hydroxy-5-methyl-5-[(1E)-2-methylbuta-1,3-dien-1-yl]thiophen-2(5H)-one
-
pH and temperature not specified in the publication
0.0138
(5R)-3-[4-([1,1'-biphenyl]-4-yl)butyl]-4-hydroxy-5-methyl-5-[(1E)-2-methylbuta-1,3-dien-1-yl]thiophen-2(5H)-one
-
pH and temperature not specified in the publication
0.008
(5R)-3-[6-([1,1'-biphenyl]-4-yl)hexanoyl]-4-hydroxy-5-methyl-5-[(1E)-2-methylbuta-1,3-dien-1-yl]thiophen-2(5H)-one
-
pH and temperature not specified in the publication
0.305
(5R)-4-hydroxy-5-methyl-5-[(1E)-2-methylbuta-1,3-dien-1-yl]-3-(propan-2-yl)thiophen-2(5H)-one
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pH and temperature not specified in the publication
0.0121
(5R)-4-hydroxy-5-methyl-5-[(1E)-2-methylbuta-1,3-dien-1-yl]-3-(trifluoroacetyl)thiophen-2(5H)-one
-
pH and temperature not specified in the publication
0.0928
(5R)-4-hydroxy-5-methyl-5-[(1E)-2-methylbuta-1,3-dien-1-yl]-3-[2-(4-methylphenyl)ethyl]thiophen-2(5H)-one
-
pH and temperature not specified in the publication
0.047
(5R)-4-hydroxy-5-methyl-5-[(1E)-2-methylbuta-1,3-dien-1-yl]thiophen-2(5H)-one
-
pH and temperature not specified in the publication
0.102
2-[(5R)-4-hydroxy-5-methyl-5-[(1E)-2-methylbuta-1,3-dien-1-yl]-2-oxo-2,5-dihydrothiophene-3-carbonyl]benzoic acid
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pH and temperature not specified in the publication
0.032
4-[(4-fluorobenzene-1-sulfonyl)amino]-N-[[1-(4-[(5R)-4-hydroxy-5-methyl-5-[(1E)-2-methylbuta-1,3-dien-1-yl]-2-oxo-2,5-dihydrothiophen-3-yl]butyl)-1H-1,2,3-triazol-4-yl]methyl]benzamide
-
pH and temperature not specified in the publication
0.0219
methyl (5R)-4-hydroxy-5-methyl-5-[(1E)-2-methylbuta-1,3-dien-1-yl]-2-oxo-2,5-dihydrothiophene-3-carboxylate
-
pH and temperature not specified in the publication
0.1754
thiolactomycin
-
pH and temperature not specified in the publication
