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1.14.19.64: (S)-stylopine synthase

This is an abbreviated version!
For detailed information about (S)-stylopine synthase, go to the full flat file.

Word Map on EC 1.14.19.64

Reaction

(S)-cheilanthifoline
+
[reduced NADPH-hemoprotein reductase]
+
O2
=
(S)-Stylopine
+
[oxidized NADPH-hemoprotein reductase]
+ 2 H2O

Synonyms

(S)-cheilanthifoline oxidase (methylenedioxy-bridge-forming), CYP719A13, CYP719A2, CYP719A2/A3, CYP719A3, EC 1.1.3.32, EC 1.14.21.1, methylenedioxy bridge-forming enzyme, stylopine synthase, synthase, (S)-stylopine

ECTree

     1 Oxidoreductases
         1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
             1.14.19 With oxidation of a pair of donors resulting in the reduction of O2 to two molecules of water
                1.14.19.64 (S)-stylopine synthase

Cofactor

Cofactor on EC 1.14.19.64 - (S)-stylopine synthase

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COFACTOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
cytochrome P450
-
the enzyme is a cytochrome P450 dependent monooxygenase
-
FAD
-
0.004 mM, together with the optimal concentration of NADPH, 0.2 mM, enhances activity by 50%
FMN
-
0.004 mM, together with the optimal concentration of NADPH, 0.2 mM, enhances activity by 50%
NADPH-hemoprotein reductase
-
-