1.14.14.95: germacrene A hydroxylase
This is an abbreviated version!
For detailed information about germacrene A hydroxylase, go to the full flat file.
Word Map on EC 1.14.14.95
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1.14.14.95
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sesquiterpene
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lactone
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costunolide
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asteraceae
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synthases
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terpene
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cos
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feverfew
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chicory
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parthenolide
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1-deoxy-d-xylulose-5-phosphate
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spinosa
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reductoisomerase
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tanacetum
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benthamiana
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amorphadiene
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artemisinic
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+-germacrene
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parthenium
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sunflower
- 1.14.14.95
-
sesquiterpene
- lactone
- costunolide
- asteraceae
- synthases
-
terpene
- cos
- feverfew
- chicory
- parthenolide
- 1-deoxy-d-xylulose-5-phosphate
- spinosa
- reductoisomerase
-
tanacetum
- benthamiana
-
amorphadiene
-
artemisinic
-
+-germacrene
- parthenium
- sunflower
Reaction
+ 3 [reduced NADPH-hemoprotein reductase] + 3 O2 = + 3 [oxidized NADPH-hemoprotein reductase] + 4 H2O
Synonyms
(+)-germacrene A hydroxylase, EC 1.1.1.314, EC 1.14.13.123, GAO, germacrene A oxidase, NADP+-dependent sesquiterpenoid dehydrogenase
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Reference
Reference on EC 1.14.14.95 - germacrene A hydroxylase
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Nguyen, D.; Goepfert, J.; Ikezawa, N.; MacNevin, G.; Kathiresan, M.; Conrad, J.; Spring, O.; Ro, D.
Biochemical conservation and evolution of germacrene A oxidase in Asteraceae
J. Biol. Chem.
285
16588-16598
2010
Lactuca sativa (D5J9U8), Cichorium intybus (D5JBW8), Cichorium intybus, Saussurea costus (D5JBW9), Helianthus annuus (D5JBX0), Barnadesia spinosa (D5JBX1), Barnadesia spinosa
De Kraker, K.J.; Franssen, M.; Dalm, M.; de, G.A.; Bouwmeester, H.
Biosynthesis of germacrene A carboxylic acid in chicory roots. Demonstration of a cytochrome P450 (+)-germacrene a hydroxylase and NADP+-dependent sesquiterpenoid dehydrogenase(s) involved in sesquiterpene lactone biosynthesis
Plant Physiol.
125
1930-1940
2001
Cichorium intybus
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