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1.14.14.156: tryptophan N-monooxygenase

This is an abbreviated version!
For detailed information about tryptophan N-monooxygenase, go to the full flat file.

Word Map on EC 1.14.14.156

Reaction

L-tryptophan
+ 2 [reduced NADPH-hemoprotein reductase] + 2 O2 =
(E)-indol-3-ylacetaldoxime
+ 2 [oxidized NADPH-hemoprotein reductase] +
CO2
+ 3 H2O

Synonyms

CYP79B1, CYP79B1 monooxygenase, CYP79B2, CYP79B3, EC 1.14.13.125

ECTree

     1 Oxidoreductases
         1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
             1.14.14 With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
                1.14.14.156 tryptophan N-monooxygenase

Reference

Reference on EC 1.14.14.156 - tryptophan N-monooxygenase

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REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Naur, P.; Hansen, C.; Bak, S.; Hansen, B.; Jensen, N.; Nielsen, H.; Halkier, B.
CYP79B1 from Sinapis alba converts tryptophan to indole-3-acetaldoxime
Arch. Biochem. Biophys.
409
235-241
2003
Sinapis alba
Manually annotated by BRENDA team
Glawischnig, E.
The role of cytochrome P450 enzymes in the biosynthesis of camalexin
Biochem. Soc. Trans.
34
1206-1208
2006
Arabidopsis thaliana
Manually annotated by BRENDA team
Zhao, Y.; Hull, A.; Gupta, N.; Goss, K.; Alonso, J.; Ecker, J.; Normanly, J.; Chory, J.; Celenza, J.
Trp-dependent auxin biosynthesis in Arabidopsis: Involvement of cytochrome P450s CYP79B2 and CYP79B3
Genes Dev.
16
3100-3112
2002
Arabidopsis thaliana
Manually annotated by BRENDA team
Mikkelsen, M.; Hansen, C.; Wittstock, U.; Halkier, B.
Cytochrome P450 CYP79B2 from Arabidopsis catalyzes the conversion of tryptophan to indole-3-acetaldoxime, a precursor of indole glucosinolates and indole-3-acetic acid
J. Biol. Chem.
275
33712-33717
2000
Arabidopsis thaliana (O81346)
Manually annotated by BRENDA team
Sanchez-Vallet, A.; Ramos, B.; Bednarek, P.; Lopez, G.; Pislewska-Bednarek, M.; Schulze-Lefert, P.; Molina, A.
Tryptophan-derived secondary metabolites in Arabidopsis thaliana confer non-host resistance to necrotrophic Plectosphaerella cucumerina fungi
Plant J.
63
115-127
2010
Arabidopsis thaliana
Manually annotated by BRENDA team
Mikkelsen, M.; Petersen, B.; Glawischnig, E.; Jensen, A.; Andreasson, E.; Halkier, B.
Modulation of CYP79 genes and glucosinolate profiles in Arabidopsis by defense signaling pathways
Plant Physiol.
131
298-308
2003
Arabidopsis thaliana
Manually annotated by BRENDA team
Glawischnig, E.; Hansen, B.; Olsen, C.; Halkier, B.
Camalexin is synthesized from indole-3-acetaldoxime, a key branching point between primary and secondary metabolism in Arabidopsis
Proc. Natl. Acad. Sci. USA
101
8245-8250
2004
Arabidopsis thaliana
Manually annotated by BRENDA team
Hull, A.; Vij, R.; Celenza, J.
Arabidopsis cytochrome P450s that catalyze the first step of tryptophan-dependent indole-3-acetic acid biosynthesis
Proc. Natl. Acad. Sci. USA
97
2379-2384
2000
Arabidopsis thaliana (O81346), Arabidopsis thaliana (Q501D8)
Manually annotated by BRENDA team