1.17.98.4: formate dehydrogenase (hydrogenase)

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For detailed information about formate dehydrogenase (hydrogenase), go to the full flat file.

Reaction

Synonyms

benzylviologen-linked formate dehydrogenase, EC 1.1.99.33, EC 1.17.99.7, Fdh-H, FDH-O, fdhF gene product, FDHH, formate dehydrogenase (formate-hydrogen-lyase-linked), formate dehydrogenase H, formate dehydrogenase O, formate hydrogenlyase, methylviologen-dependent formate dehydrogenase, molybdenum-containing formate dehydrogenase H

ECTree

     1 Oxidoreductases

         1.17 Acting on CH or CH₂ groups

             1.17.98 With other, known, physiological acceptors

                1.17.98.4 formate dehydrogenase (hydrogenase)

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Results	in table
2	Activating Compound
629	AA Sequence
2	Cloned(Commentary)
5	Cofactor
2	Crystallization (Commentary)
2	Expression
1	General Information
2	General Stability
19	Inhibitors
2	Ki Value [mM]
5	KM Value [mM]
2	Localization
23	Metals/Ions
3	Molecular Weight [Da]
10	Natural Substrates/ Products (Substrates)
31	Organism
4	Oxidation Stability
3	Pathway
1	PDB ID
6	pH Optimum
2	pH Range
7	pH Stability
2	Protein Variants
6	Purification (Commentary)
1	Reaction
27	Reference
3	Source Tissue
3	Specific Activity [micromol/min/mg]
32	Substrates and Products (Substrate)
6	Subunits
28	Synonyms
1	Systematic Name
3	Temperature Optimum [°C]
2	Turnover Number [1/s]

Expression

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Expression on EC 1.17.98.4 - formate dehydrogenase (hydrogenase)

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EXPRESSION

ORGANISM

UNIPROT

LITERATURE

high levels of formate dehydrogenase are observed in strain HF only when these cells are grown with formate in the absence of H2. In all strains two- to threefold fluctuations of both hydrogenase and formate dehydrogenase cell-free activities are observed during growth, with peak activities reached in the middle of the exponential phase

2 entries

high levels of formate dehydrogenase are observed in strain HF only when these cells are grown with formate in the absence of H2. In all strains two- to threefold fluctuations of both hydrogenase and formate dehydrogenase cell-free activities are observed during growth, with peak activities reached in the middle of the exponential phase

Methanothermococcus thermolithotrophicus

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727718

high levels of formate dehydrogenase are observed in strain HF only when these cells are grown with formate in the absence of H2. In all strains two- to threefold fluctuations of both hydrogenase and formate dehydrogenase cell-free activities are observed during growth, with peak activities reached in the middle of the exponential phase

Methanothermococcus thermolithotrophicus HF

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