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1.14.19.59: tryptophan 6-halogenase

This is an abbreviated version!
For detailed information about tryptophan 6-halogenase, go to the full flat file.

Word Map on EC 1.14.19.59

Reaction

D-tryptophan
+
FADH2
+
chloride
+
O2
+
H+
=
6-chloro-D-tryptophan
+
FAD
+ 2 H2O

Synonyms

sttH, Thal, ThdH

ECTree

     1 Oxidoreductases
         1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
             1.14.19 With oxidation of a pair of donors resulting in the reduction of O2 to two molecules of water
                1.14.19.59 tryptophan 6-halogenase

KM Value

KM Value on EC 1.14.19.59 - tryptophan 6-halogenase

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KM VALUE [mM]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
1.075
anthranilamide
wild-type enzyme, pH and temperature not specified in the publication
1.32
bromide
pH 7.2, 30°C
2.98
chloride
pH 7.2, 30°C
0.31
D-tryptophan
pH 7.2, 30°C
0.241
kynurenine
wild-type enzyme, pH and temperature not specified in the publication
0.0008 - 0.11
L-tryptophan