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1.14.14.162: flavanone 2-hydroxylase

This is an abbreviated version!
For detailed information about flavanone 2-hydroxylase, go to the full flat file.

Word Map on EC 1.14.14.162

Reaction

a flavanone
+
[reduced NADPH-hemoprotein reductase]
+
O2
=
a 2-hydroxyflavanone
+
[oxidized NADPH-hemoprotein reductase]
+
H2O

Synonyms

(2S)-flavanone 2-hydroxylase, CYP93G2, EC 1.14.13.87, EC 1.14.14.140, F2H, licodione synthase, liquiritigenin,[reduced NADPH-hemoprotein reductase]:oxygen oxidoreductase (licodione-forming), LS, More, Os06g01250, OsF2H

ECTree

     1 Oxidoreductases
         1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
             1.14.14 With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
                1.14.14.162 flavanone 2-hydroxylase

Systematic Name

Systematic Name on EC 1.14.14.162 - flavanone 2-hydroxylase

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SYSTEMATIC NAME
IUBMB Comments
flavanone,[reduced NADPH-hemoprotein reductase]:oxygen oxidoreductase (2-hydroxylating)
A cytochrome P-450 (heme thiolate) plant enzyme that catalyses the 2-hydroxylation of multiple flavanones such as (2S)-naringenin, (2S)-eriodictyol, (2S)-pinocembrin, and (2S)-liquiritigenin. The products are meta-stable and exist in an equilibrium with open forms such as 1-(4-hydroxyphenyl)-3-(2,4,6-trihydroxyphenyl)propane-1,3-dione.