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1.14.14.162: flavanone 2-hydroxylase

This is an abbreviated version!
For detailed information about flavanone 2-hydroxylase, go to the full flat file.

Word Map on EC 1.14.14.162

Reaction

a flavanone
+
[reduced NADPH-hemoprotein reductase]
+
O2
=
a 2-hydroxyflavanone
+
[oxidized NADPH-hemoprotein reductase]
+
H2O

Synonyms

(2S)-flavanone 2-hydroxylase, CYP93G2, EC 1.14.13.87, EC 1.14.14.140, F2H, licodione synthase, liquiritigenin,[reduced NADPH-hemoprotein reductase]:oxygen oxidoreductase (licodione-forming), LS, More, Os06g01250, OsF2H

ECTree

     1 Oxidoreductases
         1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
             1.14.14 With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
                1.14.14.162 flavanone 2-hydroxylase

Application

Application on EC 1.14.14.162 - flavanone 2-hydroxylase

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APPLICATION
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
synthesis
two-step indirect glycosylation using combinations of flavanone 2-hydroxylase and C-glycosyltransferases, to convert 2-hydroxyflavanone intermediates into the 6C-glucoside flavones isovitexin and isoorientin, and the 8C-glucoside flavones vitexin and orientin. The ratio between 6C and 8C glycosylation depended on the C-glycosyltransferase used. The indirect route resuls in mixtures, similar to what has been reported for in vitro experiments