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2.3.1.308: tubulin N-terminal N-acetyltransferase NAT9

This is an abbreviated version!
For detailed information about tubulin N-terminal N-acetyltransferase NAT9, go to the full flat file.

Reaction

acetyl-CoA
+
an N-terminal-L-methionyl-[tubulin]
=
an N-terminal-Nalpha-acetyl-L-methionyl-[tubulin]
+
CoA

Synonyms

CG11539, microtubule-associated N-acetyltransferase NAT9, microtubule-associated Nat9, Mnat9, NAT9

ECTree

     2 Transferases
         2.3 Acyltransferases
             2.3.1 Transferring groups other than aminoacyl groups
                2.3.1.308 tubulin N-terminal N-acetyltransferase NAT9

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Resultsin table
1Cloned(Commentary)
2General Information
1Localization
1Organism
1Purification (Commentary)
1Reaction
1Reference
3Substrates and Products (Substrate)
1Subunits
5Synonyms
1Systematic Name

General Information

General Information on EC 2.3.1.308 - tubulin N-terminal N-acetyltransferase NAT9

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GENERAL INFORMATION
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
malfunction
-
enzyme loss of causes severe developmental defects in multiple tissues. Enzyme loss results in various spindle defects during mitosis in the syncytial embryo. Knockdown of enzyme causes apoptotic cell death in the wing disc
physiological function
-
the enzyme regulates cell signaling and microtubule stability. The enzyme is required for regulation of c-Jun N-terminal kinase signaling to promote cell survival in developing Drosophila organs