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2.1.1.320: type II protein arginine methyltransferase

This is an abbreviated version!
For detailed information about type II protein arginine methyltransferase, go to the full flat file.

Word Map on EC 2.1.1.320

Reaction

2 S-adenosyl-L-methionine +

[protein]-L-arginine
= 2 S-adenosyl-L-homocysteine +
[protein]-Nomega,Nomega'-dimethyl-L-arginine

Synonyms

At4g31120, EC 2.1.1.124, EC 2.1.1.125, EC 2.1.1.126, EC 2.1.1.23, Hsl7, Jak-binding protein 1, Janus kinase-binding protein 1, JBP1, PRMT-5, PRMT-9, PRMT15, PRMT5, PRMT7, PRMT9, protein arginine methyltransferase 5, Skb1

ECTree

     2 Transferases
         2.1 Transferring one-carbon groups
             2.1.1 Methyltransferases
                2.1.1.320 type II protein arginine methyltransferase

Activating Compound

Activating Compound on EC 2.1.1.320 - type II protein arginine methyltransferase

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ACTIVATING COMPOUND
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
PRMT7
PRMT7-mediated monomethylation of histone H4 Arg17 regulates PRMT5 activity at Arg3 in the same protein. Monomethylation at Arg-17 in histone H4 raises the general activity of PRMT5 with this substrate, but also ameliorates the low activity of PRMT5 at low substrate concentrations
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