EC Number   |
Disease |
PubMed ID |
Title of Publication |
Category |
Confidence Level |
|---|
    2.3.1.179 | Infections |
19064257 |
The fatty acid biosynthesis enzyme FabI plays a key role in the development of liver-stage malarial parasites. |
causal interaction
therapeutic application
unassigned |
4
4
0 |
| 2.3.1.179 | Infections |
19068099 |
Type II fatty acid synthesis is essential only for malaria parasite late liver stage development. |
unassigned |
0 |
| 2.3.1.179 | Malaria |
17485508 |
Mass spectrometry-based systems approach for identification of inhibitors of Plasmodium falciparum fatty acid synthase. |
ongoing research
unassigned |
1
0 |
| 2.3.1.179 | Pneumonia |
18219113 |
Surface-entropy reduction approaches to manipulate crystal forms of beta-ketoacyl acyl carrier protein synthase II from Streptococcus pneumoniae. |
unassigned |
0 |
| 2.3.1.179 | Tuberculosis |
15525558 |
Development of a scintillation proximity assay for the Mycobacterium tuberculosis KasA and KasB enzymes involved in mycolic acid biosynthesis. |
ongoing research
unassigned |
1
0 |
| 2.3.1.179 | Tuberculosis |
17174327 |
X-ray crystal structure of Mycobacterium tuberculosis beta-ketoacyl acyl carrier protein synthase II (mtKasB). |
causal interaction
ongoing research
therapeutic application
unassigned |
3
2
4
0 |
| 2.3.1.179 | Tuberculosis |
19083031 |
Homology modelling of 3-oxoacyl-acyl carrier protein synthase II from Mycobacterium tuberculosis H37Rv and molecular docking for exploration of drugs. |
unassigned |
0 |
| 2.3.1.179 | Tuberculosis |
20018879 |
Slow onset inhibition of bacterial beta-ketoacyl-acyl carrier protein synthases by thiolactomycin. |
therapeutic application
unassigned |
1
0 |
