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EC Number
Localization
Commentary
GeneOntology No.
Reference
2.4.1.66
cell surface
-
GO:0009986
AmiGO
QuickGO
722865
2.4.1.66
cytoplasm
5-10% of the total activity is surface-bound, the rest is of cytoplasmic origin
GO:0005737
AmiGO
QuickGO
636787
2.4.1.66
endoplasmic reticulum
-
GO:0005783
AmiGO
QuickGO
675031
2.4.1.66
endoplasmic reticulum
located within the cisternae of the endoplasmic reticulum
GO:0005783
AmiGO
QuickGO
636777
,
636781
2.4.1.66
endoplasmic reticulum
rough and smooth
GO:0005783
AmiGO
QuickGO
636773
,
636774
2.4.1.66
endoplasmic reticulum
secretion of the enzyme from the endoplasmic reticulum to the extracellular space occurs via two secretory pathways, which generate two glycoforms. Enzyme molecules found in the cell medium are secreted through the Golgi complex, and the secretion is dependent on lysyl hydroxylase 3 glycosyltransferase activity. Enzyme found on the cell surface bypasses the Golgi complex
GO:0005783
AmiGO
QuickGO
722865
2.4.1.66
extracellular
-
-
699120
,
722865
2.4.1.66
extracellular
liver enzyme
-
675031
2.4.1.66
Golgi apparatus
-
GO:0005794
AmiGO
QuickGO
636773
,
636774
2.4.1.66
intracellular
-
GO:0005622
AmiGO
QuickGO
636781
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