2.3.1.95: trihydroxystilbene synthase
This is an abbreviated version!
For detailed information about trihydroxystilbene synthase, go to the full flat file.
Word Map on EC 2.3.1.95
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2.3.1.95
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vitis
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grapevine
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vinifera
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grape
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chalcone
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phytoalexins
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berry
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arachis
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hypogaea
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trans-resveratrol
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mildew
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pinosylvin
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piceid
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tetraketide
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powdery
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viticola
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stilbenoids
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p-coumaroyl-coa
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4-coumarate
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amurensis
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plasmopara
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vineyard
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pinot
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4-coumarate:coa
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chs-like
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pseudoreticulata
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uncinula
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trans-piceid
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cabernet
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riparia
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pgips
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agriculture
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synthesis
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analysis
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pharmacology
- 2.3.1.95
- vitis
-
grapevine
- vinifera
- grape
- chalcone
-
phytoalexins
- berry
- arachis
- hypogaea
- trans-resveratrol
- mildew
- pinosylvin
- piceid
-
tetraketide
-
powdery
- viticola
-
stilbenoids
- p-coumaroyl-coa
- 4-coumarate
- amurensis
-
plasmopara
-
vineyard
-
pinot
-
4-coumarate:coa
-
chs-like
- pseudoreticulata
-
uncinula
-
trans-piceid
-
cabernet
- riparia
-
pgips
- agriculture
- synthesis
- analysis
- pharmacology
Reaction
3 malonyl-CoA + = 4 CoA + + 4 CO2
Synonyms
AhSTS3, malonyl-CoA:4-coumaroyl-CoA malonyltransferase, resveratrol synthase, SbCHS8, SbSTS1, stilbene synthase, stilbene synthase 1, stilbene synthase 3, stilbene synthase-type polyketide synthase enzyme, STS, STS-type PKS enzyme, STS1, STS29, STS6, STS7, synthase, resveratrol, VIT_16s0100g01030, VIT_16s0100g01040, vst1
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General Information
General Information on EC 2.3.1.95 - trihydroxystilbene synthase
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evolution
stilbene synthase 3 from Arachis hypogaea represents a type III PKS enzyme
metabolism
physiological function
stilbene synthase is a pivotal enzyme that catalyzes the biosynthesis of resveratrol
metabolism
stilbene synthase, STS, catalyzes the biosynthesis of resveratrol
expression of Arachis hypogaea resveratrol synthase in Oryza sativa. Compared to the wild-type rice, in which trans-resveratrol is undetectable, in transgenic rice, the trans-resveratrol achieves up to 0.697 microg/g fresh weigt in seedlings and 3.053 microg/g dry weight in seeds. The concentration of trans-resveratrol in transgenic rice seedlings can be induced up to eight or fourfold higher by ultraviolet or dark, respectively. Simultaneously, the endogenous increase of resveratrol protects the host plant from UV-C caused damage or dark-induced senescence
physiological function
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overexpression of isoform STS6 from Chinese wild type Vitis quinquangularis in Vitis vinifera Thompson. The resistance to powdery mildew (Uncinula necator) is particularly enhanced in lines most highly expressing STS6. Compared with the non-transformed controls, trans-resveratrol and other stilbene compounds are significantly increased in the transgenic lines
physiological function
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overexpression of the STS7 gene increases the resveratrol content in transgenic grape cells by 3.2-6.6 times as compared with control cells. The transformation also enhances dry biomass accumulation, resveratrol production therefore increases significantly, by 4.7-9.7 times, as compared with control cells
physiological function
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leaves from fusion proteins STS29-GFP-expressing lines display more serious UV damage, showing withering and marginal scorching phenotype, and decreased content of H2O2, compared to control. Overexpression of STS29 alters the expression of genes related to redox regulation, stilbene biosynthesis and light stimulus. Coexpression of STS29-GFP with glycolate oxidase 1 decreases the content of H2O2 in Arabidopsis mesophyll protoplasts
physiological function
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the allele from the wild Chinese grapevine can confer accumulation of stilbenes and resistance against the powdery mildew Golovinomyces cichoracearum, whereas the allele from the vinifera cultivar cannot
physiological function
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overexpression of isoform STS6 from Chinese wild type Vitis quinquangularis in Vitis vinifera Thompson. The resistance to powdery mildew (Uncinula necator) is particularly enhanced in lines most highly expressing STS6. Compared with the non-transformed controls, trans-resveratrol and other stilbene compounds are significantly increased in the transgenic lines
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physiological function
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overexpression of the STS7 gene increases the resveratrol content in transgenic grape cells by 3.2-6.6 times as compared with control cells. The transformation also enhances dry biomass accumulation, resveratrol production therefore increases significantly, by 4.7-9.7 times, as compared with control cells
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