2.1.1.103: phosphoethanolamine N-methyltransferase
This is an abbreviated version!
For detailed information about phosphoethanolamine N-methyltransferase, go to the full flat file.
![](word_maps/png/2_1_1_103.png)
Word Map on EC 2.1.1.103
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2.1.1.103
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phosphatidylcholine
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phosphocholine
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choline
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phospholipid
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plasmodium
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falciparum
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malaria
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betaine
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s-adenosylhomocysteine
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plant-like
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osmoprotectant
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cdp-choline
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s-adenosylmethionine-dependent
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transmethylation
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medicine
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halophyte
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s-adenosyl-l-methionine-dependent
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nematicide
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amodiaquine
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drug development
- 2.1.1.103
- phosphatidylcholine
- phosphocholine
- choline
- phospholipid
- plasmodium
- falciparum
- malaria
- betaine
- s-adenosylhomocysteine
-
plant-like
-
osmoprotectant
- cdp-choline
-
s-adenosylmethionine-dependent
-
transmethylation
- medicine
-
halophyte
-
s-adenosyl-l-methionine-dependent
-
nematicide
- amodiaquine
- drug development
Reaction
Synonyms
AtNMT1, DPR2, More, NMT1, NMT2, PEAMT, PEAMT1, Pfpmt, phosphodimethylethanolamine methyltransferase, phosphoethanolamine methyltransferase, phosphoethanolamine N-methyltransferase, phosphoethanolamine-N-methyltransferases, phosphomethylethanolamine N-methyltransferase, PMEAMT, PMT, PMT-1, PMT1, PMT2, PVX_083045, S-adenosyl-L-methionine:phosphoethanolamine N-methyltransferase, SoPEAMT
ECTree
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IC50 Value
IC50 Value on EC 2.1.1.103 - phosphoethanolamine N-methyltransferase
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0.009
(3S)-1-(4-hydroxyphenyl)-N-[(2S)-1-[[2-(1H-indol-3-yl)ethyl]amino]-1-oxopropan-2-yl]-5-oxopyrrolidine-3-carboxamide
Plasmodium falciparum
pH not specified in the publication, temperature not specified in the publication
0.013
diphenhydramine
Haemonchus contortus
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isozyme PMT2, in 0.1 M HEPES (pH 8.0), 2 mM Na2EDTA, 10% glycerol, at 25°C
0.003
N-[5-[(9,10-dimethoxy-4-oxo-6,7-dihydro-4H-pyrimido[6,1-a]isoquinolin-2-yl)amino]pentyl]propanamide
Plasmodium falciparum
pH not specified in the publication, temperature not specified in the publication
0.46
primaquine
Plasmodium falciparum
pH and temperature not specified in the publication
0.0028
Haemonchus contortus
combination of isoforms PMT1/PMT2, 24°C, pH not specified in the publication
0.0059
7-(3,5-dibromo-4-hydroxyphenethylamino)quinoline-5,8-dione
Haemonchus contortus
isoform PMT1 alone, 24°C, pH not specified in the publication
1.35
amodiaquine
Plasmodium falciparum
pH and temperature not specified in the publication
3.1
amodiaquine
Haemonchus contortus
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isozyme PMT2, in 0.1 M HEPES (pH 8.0), 2 mM Na2EDTA, 10% glycerol, at 25°C
3.4
amodiaquine
Haemonchus contortus
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isozyme PMT1, in 0.1 M HEPES (pH 8.0), 2 mM Na2EDTA, 10% glycerol, at 25°C
0.554
Chloroquine
Plasmodium falciparum
pH and temperature not specified in the publication
0.0125
Haemonchus contortus
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isozyme PMT2, in 0.1 M HEPES (pH 8.0), 2 mM Na2EDTA, 10% glycerol, at 25°C
0.1252
miltefosine
Haemonchus contortus
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isozyme PMT1, in 0.1 M HEPES (pH 8.0), 2 mM Na2EDTA, 10% glycerol, at 25°C
0.0051
Haemonchus contortus
combination of isoforms PMT1/PMT2, 24°C, pH not specified in the publication
0.0083
NSC-641296
Haemonchus contortus
isoform PMT1 alone, 24°C, pH not specified in the publication
0.0338
Haemonchus contortus
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isozyme PMT1, in 0.1 M HEPES (pH 8.0), 2 mM Na2EDTA, 10% glycerol, at 25°C
0.0915
sinefungin
Haemonchus contortus
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isozyme PMT2, in 0.1 M HEPES (pH 8.0), 2 mM Na2EDTA, 10% glycerol, at 25°C
3.5
Haemonchus contortus
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isozyme PMT2, in 0.1 M HEPES (pH 8.0), 2 mM Na2EDTA, 10% glycerol, at 25°C
23.4
tacrine
Haemonchus contortus
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isozyme PMT1, in 0.1 M HEPES (pH 8.0), 2 mM Na2EDTA, 10% glycerol, at 25°C