1.14.99.20: phylloquinone monooxygenase (2,3-epoxidizing)

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For detailed information about phylloquinone monooxygenase (2,3-epoxidizing), go to the full flat file.

Reaction

Synonyms

epoxidase, phylloquinone, oxygenase, phylloquinone mono- (2,3-epoxidizing), phylloquinone epoxidase, vitamin K 2,3-epoxidase, vitamin K epoxidase, vitamin K epoxide reductase complex subunit 1, VKORC1

ECTree

     1 Oxidoreductases

         1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen

             1.14.99 Miscellaneous

                1.14.99.20 phylloquinone monooxygenase (2,3-epoxidizing)

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Results	in table
4	Activating Compound
1	AA Sequence
1	CAS Registry Number
3	Cloned(Commentary)
7	Cofactor
4	Disease/ Diagnostics
2	General Stability
6	Inhibitors
1	KM Value [mM]
11	Localization
1	Metals/Ions
3	Molecular Weight [Da]
11	Natural Substrates/ Products (Substrates)
17	Organism
4	Protein Variants
4	Purification (Commentary)
8	Reaction
3	Reaction Type
15	Reference
11	Source Tissue
7	Specific Activity [micromol/min/mg]
4	Storage Stability
29	Substrates and Products (Substrate)
3	Subunits
7	Synonyms
1	Systematic Name
9	Temperature Optimum [°C]
1	Turnover Number [1/s]

Disease

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Disease on EC 1.14.99.20 - phylloquinone monooxygenase (2,3-epoxidizing)

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DISEASE

TITLE OF PUBLICATION

LINK TO PUBMED

Cerebral Hemorrhage

In models of intracerebral hemorrhage, rivaroxaban is superior to warfarin to limit blood brain barrier disruption and hematoma expansion.

27993122

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