1.14.19.B10: indole 3-halogenase
This is an abbreviated version!
For detailed information about indole 3-halogenase, go to the full flat file.
Reaction
Synonyms
brvH, FHal, flavin-dependent halogenase
ECTree
Advanced search results
Substrates Products
Substrates Products on EC 1.14.19.B10 - indole 3-halogenase
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
REACTION DIAGRAM
indole + FADH2 + bromide + O2 + H+
3-bromoindole + FAD + 2 H2O
-
-
-
?
indole + FADH2 + chloride + O2 + H+
3-chloroindole + FAD + 2 H2O
low activity
-
-
?
additional information
?
-
the enzyme prefers bromide to chloride as halide source. The enzyme shows no halogenation of tryptophan, neither in presence of chloride nor in presence of bromide and has no activity with 5-hydroxytryptohan, tryptophol, indole-3-propionic acid, and indole-3-acetonitrile
-
-
-