1.14.14.96: 5-O-(4-coumaroyl)-D-quinate 3'-monooxygenase
This is an abbreviated version!
For detailed information about 5-O-(4-coumaroyl)-D-quinate 3'-monooxygenase, go to the full flat file.
Word Map on EC 1.14.14.96
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1.14.14.96
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prostaglandin
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cyclooxygenase
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celecoxib
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nsaid
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nonsteroidal
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arachidonic
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nf-kappab
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rofecoxib
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lipopolysaccharide
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prostanoids
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indomethacin
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il-1beta
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lps-induced
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nonselective
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thromboxane
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chemoprevention
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aspirin
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prostacyclin
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ibuprofen
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eicosanoids
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interleukin-1beta
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lps-stimulated
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signal-regulated
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naproxen
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analgesic
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diclofenac
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placebo
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rheumatoid
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microvessels
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meloxicam
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coxibs
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nimesulide
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factor-kappab
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osteoarthritis
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polyp
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adenomatous
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6-keto-prostaglandin
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synthase-1
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hyperalgesia
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piroxicam
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5-lipoxygenase
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polyposis
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macula
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ulcerogenic
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gastroprotective
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densa
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carrageenan-induced
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cyclo-oxygenase-2
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il-1beta-induced
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biofuel production
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mpges-1
- 1.14.14.96
- prostaglandin
-
cyclooxygenase
- celecoxib
-
nsaid
-
nonsteroidal
-
arachidonic
-
nf-kappab
- rofecoxib
- lipopolysaccharide
-
prostanoids
- indomethacin
-
il-1beta
-
lps-induced
-
nonselective
-
thromboxane
-
chemoprevention
- aspirin
- prostacyclin
- ibuprofen
-
eicosanoids
-
interleukin-1beta
-
lps-stimulated
-
signal-regulated
- naproxen
-
analgesic
- diclofenac
-
placebo
-
rheumatoid
-
microvessels
- meloxicam
-
coxibs
- nimesulide
-
factor-kappab
-
osteoarthritis
-
polyp
-
adenomatous
-
6-keto-prostaglandin
-
synthase-1
-
hyperalgesia
- piroxicam
-
5-lipoxygenase
-
polyposis
-
macula
-
ulcerogenic
-
gastroprotective
-
densa
-
carrageenan-induced
-
cyclo-oxygenase-2
-
il-1beta-induced
- biofuel production
- mpges-1
Reaction
Synonyms
5-O-(4-coumaroyl)-D-quinate/shikimate 3'-hydroxylase, coumaroylquinate (coumaroylshikimate) 3'-monooxygenase, EC 1.14.13.36, p-coumaroyl quinate/shikimate 3'-hydroxylase
ECTree
1.14.14.96 5-O-(4-coumaroyl)-D-quinate 3'-monooxygenaseAdvanced search results
results (
results (Natural Substrates Products
Natural Substrates Products on EC 1.14.14.96 - 5-O-(4-coumaroyl)-D-quinate 3'-monooxygenase
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NATURAL SUBSTRATE 
NATURAL PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate)
(Substrate)
LITERATURE
(Substrate)
(Substrate)
COMMENTARY
(Product)
(Product)
LITERATURE
(Product)
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
r=reversible
ir=irreversible
?=not specified
trans-5-O-(4-coumaroyl)-D-quinate + [reduced NADPH-hemoprotein reductase] + O2
trans-5-O-caffeoyl-D-quinate + [oxidized NADPH-hemoprotein reductase] + H2O
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specific for the trans isomer, final step in the chlorogenic acid pathway, reaction is greatly enhanced by irradiation with blue/uv light
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?
trans-5-O-(4-coumaroyl)shikimate + [reduced NADPH-hemoprotein reductase] + O2
trans-5-O-caffeoylshikimate + [oxidized NADPH-hemoprotein reductase] + H2O
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70% of the activity compared to trans-5-O-(4-coumaroyl)-D-quinate, specific for the trans isomer
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?
