1.14.14.77: phenylacetonitrile alpha-monooxygenase

This is an abbreviated version!
For detailed information about phenylacetonitrile alpha-monooxygenase, go to the full flat file.

Reaction

Synonyms

CYP3201B1

ECTree

1 Oxidoreductases

1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen

1.14.14 With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor

1.14.14.77 phenylacetonitrile alpha-monooxygenase

Advanced search results

Do not include text mining results

Include

results (more...)

Include

results (more...)

Results	in table
2	AA Sequence
1	Cloned(Commentary)
1	Cofactor
4	kcat/KM [mM/s]
4	KM Value [mM]
6	Natural Substrates/ Products (Substrates)
1	Organism
1	Pathway
1	pH Optimum
1	pH Stability
1	Reaction
1	Reference
6	Substrates and Products (Substrate)
2	Synonyms
1	Systematic Name
1	Temperature Optimum [°C]
1	Temperature Stability [°C]
4	Turnover Number [1/s]

Systematic Name

print visible entries

print all entries

Systematic Name on EC 1.14.14.77 - phenylacetonitrile alpha-monooxygenase

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.

top print hide

Go to Systematic Name Search

phenylacetonitrile,[reduced NADPH-hemoprotein reductase]:oxygen oxidoreductase [(R)-mandelonitrile-forming]

The enzyme has been characterized from the cyanogenic millipede Chamberlinius hualienensis. Unlike plant enzymes that can catalyse this reaction (EC 1.14.14.44, phenylacetaldehyde oxime monooxygenase), this enzyme cannot act on phenylacetaldehyde oximes. It can accept (4-hydroxyphenyl)acetonitrile, (2-methylphenyl)acetonitrile, and (3-methylphenyl)acetonitrile as substrates at a lower rate.