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1.14.14.177: ultra-long-chain fatty acid omega-hydroxylase

This is an abbreviated version!
For detailed information about ultra-long-chain fatty acid omega-hydroxylase, go to the full flat file.

Word Map on EC 1.14.14.177

Reaction

an ultra-long-chain fatty acid
+
[reduced NADPH---hemoprotein reductase]
+
O2
=
an ultra-long-chain omega-hydroxy fatty acid
+
[Oxidized NADPH---hemoprotein reductase]
+
H2O

Synonyms

CYP4F22

ECTree

     1 Oxidoreductases
         1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
             1.14.14 With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
                1.14.14.177 ultra-long-chain fatty acid omega-hydroxylase

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Resultsin table
1AA Sequence
1Application
51Disease/ Diagnostics
1General Information
2Localization
1Organism
1Pathway
1Reaction
1Reference
2Source Tissue
2Substrates and Products (Substrate)
2Synonyms
1Systematic Name

Application

Application on EC 1.14.14.177 - ultra-long-chain fatty acid omega-hydroxylase

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APPLICATION
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
medicine
CYP4F22 is one of the autosomal recessive congenital ichthyosis-causative genes. Ichthyosis-mutant proteins exhibit reduced enzyme activity. Lipid analysis of a patient with ichthyosis shows a drastic decrease in acylceramide production