1.14.14.167: (13S,14R)-13-O-acetyl-1-hydroxy-N-methylcanadine 8-hydroxylase

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For detailed information about (13S,14R)-13-O-acetyl-1-hydroxy-N-methylcanadine 8-hydroxylase, go to the full flat file.

Reaction

(13S,14R)-13-O-acetyl-1,8-dihydroxy-N-methylcanadine

Synonyms

1-hydroxy-13-O-acetyl-N-methylcanadine 8-hydroxylase, CYP82X1

ECTree

1 Oxidoreductases

1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen

1.14.14 With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor

1.14.14.167 (13S,14R)-13-O-acetyl-1-hydroxy-N-methylcanadine 8-hydroxylase

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1	AA Sequence
1	Application
2	Cloned(Commentary)
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3	General Information
2	KM Value [mM]
3	Natural Substrates/ Products (Substrates)
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1	Reaction
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7	Substrates and Products (Substrate)
6	Synonyms
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Reference on EC 1.14.14.167 - (13S,14R)-13-O-acetyl-1-hydroxy-N-methylcanadine 8-hydroxylase

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748729

Dang, T.; Chen, X.; Facchini, P.

Acetylation serves as a protective group in noscapine biosynthesis in opium poppy

Nat. Chem. Biol.

104-106

2015

Papaver somniferum (I3V6B7)

25485687

748743

Li, Y.; Smolke, C.

Engineering biosynthesis of the anticancer alkaloid noscapine in yeast

Nat. Commun.

12137

2016

Papaver somniferum (I3V6B7)

27378283

749191

Li, Y.; Li, S.; Thodey, K.; Trenchard, I.; Cravens, A.; Smolke, C.

Complete biosynthesis of noscapine and halogenated alkaloids in yeast

Proc. Natl. Acad. Sci. USA

115

E3922-E3931

2018

Papaver somniferum (I3V6B7)

29610307