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1.14.14.135: glyceollin synthase

This is an abbreviated version!
For detailed information about glyceollin synthase, go to the full flat file.

Reaction

2-dimethylallyl-(6aS,11aS)-3,6a,9-trihydroxypterocarpan
+
[reduced NADPH-hemoprotein reductase]
+
O2
=
glyceollin II
+
[oxidized NADPH-hemoprotein reductase]
+ 2 H2O

Synonyms

dimethylallyl-3,6a,9-trihydroxypterocarpan cyclase, EC 1.14.13.85

ECTree

     1 Oxidoreductases
         1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
             1.14.14 With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
                1.14.14.135 glyceollin synthase

Inhibitors

Inhibitors on EC 1.14.14.135 - glyceollin synthase

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INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
Ancymidol
-
0.01 mM: 15% inhibition, 0.1 mM: 85% inhibition
BAS 110
-
0.1 mM, 15% inhibition
BAS 111
-
0.1 mM, 39% inhibition
CO
-
inhibits in a white light-reversible manner in the presence of oxygen
cytochrome c
-
0.01 mM: 25% inhibition, 0.025 mM: 64% inhibition, 0.05 mM: 85% inhibition
glyceollin
-
product inhibition, 0.058 mM, 50% inhibition
ketoconazol
-
0.01 mM: 34% inhibition, 0.1 mM: 100% inhibition
LAB 978
-
0.01 mM: 17% inhibition, 0.1 mM: 49% inhibition
Metyrapone
-
0.01 mM: 15% inhibition, 0.1 mM: 37% inhibition
NADP+
-
strong inhibition by NADP+ at low NADPH concentrations
potassium isothiocyanate
-
0.01 mM: 19% inhibition, 0.1 mM: 73% inhibition, 1 mM: 100% inhibition
SKF 525
-
0.1 mM: 11% inhibition, 1 mM: 100% inhibition
tetcyclasis
-
0.01 mM: 9% inhibition, 0.1 mM: 67% inhibition