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1.14.13.251: glycine betaine monooxygenase

This is an abbreviated version!
For detailed information about glycine betaine monooxygenase, go to the full flat file.

Reaction

glycine betaine
+
NADH
+
H+
+
O2
=
N,N-dimethylglycine
+
formaldehyde
+
NAD+
+
H2O

Synonyms

BmoA, bmoAB, BmoB, Csal_1004, Csal_1005, GbcA, gbcAB, GbcB, glycine betaine dioxygenase, PA5410, PA5411

ECTree

     1 Oxidoreductases
         1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
             1.14.13 With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor
                1.14.13.251 glycine betaine monooxygenase

Systematic Name

Systematic Name on EC 1.14.13.251 - glycine betaine monooxygenase

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SYSTEMATIC NAME
IUBMB Comments
glycine betaine,NADH:oxygen oxidoreductase (demethylating)
The enzyme, characterized from the bacteria Pseudomonas aeruginosa and Chromohalobacter salexigens, is involved in a degradation pathway of glycine betaine. It is composed of two subunits - a ferredoxin reductase component that contains FAD, and a terminal oxygenase component that contains a [2Fe-2S] Rieske-type iron-sulfur cluster and a nonheme iron centre.