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EC Number Protein Variants Commentary Reference
Show all pathways known for 2.3.3.21Display the word mapDisplay the reaction diagram Show all sequences 2.3.3.21D17A construct for kinetic and mutagenesis studies of LiCMS 685015
Show all pathways known for 2.3.3.21Display the word mapDisplay the reaction diagram Show all sequences 2.3.3.21D17A LiCMS mutant, caused a 34fold increase in the Km for pyruvate, and a 315fold decrease in the kcat 685015
Show all pathways known for 2.3.3.21Display the word mapDisplay the reaction diagram Show all sequences 2.3.3.21D17A mutation of the active site 685015
Show all pathways known for 2.3.3.21Display the word mapDisplay the reaction diagram Show all sequences 2.3.3.21D17N construct for kinetic and mutagenesis studies of LiCMS 685015
Show all pathways known for 2.3.3.21Display the word mapDisplay the reaction diagram Show all sequences 2.3.3.21D17N LiCMS mutant, causes a 4.4fold increase in the Km for pyruvate, and a 480fold decrease in the kcat 685015
Show all pathways known for 2.3.3.21Display the word mapDisplay the reaction diagram Show all sequences 2.3.3.21D17N mutation of the active site 685015
Show all pathways known for 2.3.3.21Display the word mapDisplay the reaction diagram Show all sequences 2.3.3.21D304A LiCMS mutant, substantially weakens the binding of both acetyl-CoA and pyruvate and also decrease the kcat value 685015
Show all pathways known for 2.3.3.21Display the word mapDisplay the reaction diagram Show all sequences 2.3.3.21D304A mutation in the C-regional region of LiCMSN 685015
Show all pathways known for 2.3.3.21Display the word mapDisplay the reaction diagram Show all sequences 2.3.3.21D404A construct for kinetic and mutagenesis studies of LiCMS 685015
Show all pathways known for 2.3.3.21Display the word mapDisplay the reaction diagram Show all sequences 2.3.3.21D431A changes hydrophobic residues at inhibitor binding site, minor effect on Km for acetyl-CoA but moderate decrease of kcat in the absence of inhibitor isoleucine, severely decreased inhibition by isoleucine (increase of IC50 and Ki values) 702132
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