EC Number   |
Substrates |
Organism |
Products |
Reversibility |
|---|
   2.4.1.80 | CDP-glucose + N-acylsphingosine |
i.e. ceramide |
Rattus norvegicus |
CDP + D-glucosyl-N-acylsphingosine |
i.e. glucosylceramide |
? |
| 2.4.1.80 | more |
octanoyl dihydrosphingosine, decanoyl sphingosine, and stearoyl sphingosine are poor substrates |
Homo sapiens |
? |
- |
? |
| 2.4.1.80 | more |
enzyme decreases apoptosis and induces multidrug resistance, functional interaction with RTN-1C modulates enzyme activity and regulates chemotherapeutic-induced apoptosis in neuroepithelioma cells |
Homo sapiens |
? |
- |
? |
| 2.4.1.80 | more |
lipid profile of the parasite at different developmental stages, overview |
Plasmodium falciparum |
? |
- |
? |
| 2.4.1.80 | more |
the enzyme has dual function as negative regulator of cell death mediated by proapoptotic factors and in catalyzing the formation of glucosylceramide, the core structure of major glycosphingolipids, ceramide generation might be a signal pathway |
Drosophila melanogaster |
? |
- |
? |
| 2.4.1.80 | more |
NBD ceramide is used as substrate |
Homo sapiens |
? |
- |
? |
| 2.4.1.80 | TDP-glucose + N-acylsphingosine |
i.e. ceramide |
Rattus norvegicus |
TDP + D-glucosyl-N-acylsphingosine |
i.e. glucosylceramide |
? |
| 2.4.1.80 | UDP + N-{6-[(7-nitro-2,1,3-benzoxadiazol-4-yl)amino]hexanoyl}sphingosine |
- |
Homo sapiens |
UDP + ? |
- |
? |
| 2.4.1.80 | UDP-glucose + 6-(((N-7-nitrobenz-2-oxa-1,3-diazol-4yl)amino)caproyl)sphingosine |
- |
Homo sapiens |
UDP + ? |
- |
? |
| 2.4.1.80 | UDP-glucose + 6-([(N-7-nitrobenz-2-oxa-1,3-diazol-4-yl)amino]caproyl)sphingosine |
- |
Drosophila melanogaster |
UDP + N-(6-((4-nitrobenz-2-oxa-1,3-diazol-7-yl)amino)caproyl)-O1-D-glucosyl-sphingosine |
- |
? |
