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EC Number Renatured (Commentary) Reference
Show all pathways known for 1.17.1.4Display the word mapDisplay the reaction diagram Show all sequences 1.17.1.4conversion of xanthine oxidoreductase from dehydrogenase to oxidase form occurs in the presence of guanidine-HCl or urea. Both forms are in a thermodynamic equilibrium that can be shifted by disruption of the stabilizing amino acid cluster with a denaturant 689276
Show all pathways known for 1.17.1.4Display the word mapDisplay the reaction diagram Show all sequences 1.17.1.4conversion of xanthine oxidoreductase from dehydrogenase to oxidase form occurs in the presence of guanidine-HCl or urea. Both forms are in a thermodynamic equilibrium that can be shifted by disruption of the stabilizing amino acid cluster with a denaturant. Above 3 M guandine-HCl, even xanthine oxidase activity decreases drastically, but the xanthine oxidase form treated with 1.5 M can be completely reconverted into xanthine dehydrogenase by dialysis 689276
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