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EC Number General Information Commentary Reference
Display the word mapDisplay the reaction diagram Show all sequences 2.4.1.40physiological function the deletion of exon 3 or 4, but not of exon 2 or 5, of human GTA transcripts bestows moderate Forssman glycolipid synthase activity. Strong Forssman glycolipid synthase activity is attained, in addition to GTA and GTB activities, by cointroducing one of those deletions and the replacement of the LeuGlyGly tripeptide sequence at codons 266 to 268 by GlyGlyAla substitution, i.e. to the residues of Forssman glycolipid synthase 758457
Display the word mapDisplay the reaction diagram Show all sequences 2.4.1.40physiological function when Von Willebrand factor expressing H-antigen (H-VWF) from blood group O and bovine serum albumin conjugated with H-antigen (H-BSA) are incubated with recombinant alpha1-3-N-acetylgalactosaminyltransferase (rA-transferase) and A-plasma and and UDP-GalNAc, both H-VWF and H-BSA acquire the A-antigen. Incubation with A-plasma very weakly converts the H-antigen on BSA and Von Willebrand factor only in the presence of supplemented UDP-GalNAc. This conversion is enhanced on desialylation of H-VWF 756977
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