EC Number   |
General Information |
Reference |
|---|
   2.3.1.48 | evolution |
according to the allosteric ligand type of the ACT domain, members of AAPatA family are divided into two groups, the asparagine (Asn)-activated PatA and the cysteine (Cys)-activated PatA. The former exists only in Streptomyces, the latter are distributed in other actinobacteria (Pseudonocardiaceae, Micromonosporaceae, Nocardiopsaceae, and Streptosporangiaceae) |
-, 756227 |
| 2.3.1.48 | evolution |
acetyltransferases are very well conserved through evolution |
735770 |
| 2.3.1.48 | evolution |
HBO1 (also known as KAT7, MYST2) is a canonical member of the MYST (MOZ, Ybf1/Sas3, Sas2 and Tip60) acetyltransferase family. HBO1 contains the MYST domain that is a highly conserved acetyltransferase domain shared by the MYST family such as MYST1 (MOF/KAT8), MYST2 (HBO1/KAT7), and MYST3 (MOZ/KAT6A). HBO1 comprises a cervical-loop structure proximity to the MYST domain that mediates the interaction with the N-terminal region (residues 31-80) of BRPF2 (also known as BRD1), for BRPF2 is a cofactor directing HBO1 binding to the histone |
756418 |
| 2.3.1.48 | evolution |
histone acetyltransferase KAT8 is a member of the MYST family |
736051 |
| 2.3.1.48 | evolution |
histone acetyltransferase p300 is a member of the p300/CBP family |
736051 |
| 2.3.1.48 | evolution |
histone acetyltransferase p300/CBP-associated factor (PCAF) belongs to GCN5 family |
735614 |
| 2.3.1.48 | evolution |
tehe enzyme belongs to the p300/CBP enzyme family |
735572 |
| 2.3.1.48 | evolution |
the Arabidopsis genome contains 12 histone acetyltransferase genes |
737004 |
| 2.3.1.48 | evolution |
the enzyme belongs to the components of transcription factor complexes |
756850 |
| 2.3.1.48 | evolution |
the enzyme belongs to the GCN5-family of lysine acetyltransferases |
737148 |
