EC Number |
Expression |
Reference |
---|
2.1.1.37 | down |
nicotine decreases DNA methyltransferase 1 expression in in cortical and hippocampal but not in striatal GABAergic interneurons, while DNMT1 mRNA content in the liver fails to change after nicotine treatment, overview. Mecamylamine but not hexamethonium blocks nicotine-induced downregulation of DNMT1 expression. The downregulation proceeds via selective stimulation of nicotinic acetylcholine receptor, nAChR, overview |
700956 |
2.1.1.37 | more |
Dnmt3a mRNA levels are comparable between the two photoperiod groups during the first week of treatment but after 30 and 120 days of exposure to continuous light, fish from the constant illumination group express Dnmt3a at 1.3- and 1.7fold higher levels than their natural photoperiod conditions counterparts |
733934 |
2.1.1.37 | up |
Dnmt1 transcript levels show a significant increase in fast muscle of juvenile cod from the continuous light group at several time points. Transcript levels are 2fold higher at 120 days, by which point photoperiod conditions between the two light groups have become identical |
733934 |