EC Number   |
Expression |
Reference |
|---|
    1.3.5.1 | down |
1-(4-chlorophenyl)-benzo-2,5-quinone treatment decreases in the mRNA levels of succinate dehydrogenase (complex II) subunits C and D (sdhc and sdhd). The decrease in sdhc and sdhd expression is associated with a significant decrease in complex II activity and increase in mitochondrial levels of reactive oxygen species |
741795 |
| 1.3.5.1 | down |
at least 15fold downregulated in presence of acetate, 4-hydroxybutyrate, succinate or pyruvate |
-, 727749 |
| 1.3.5.1 | down |
both succinate dehydrogenase, SDH, and succinate:ubiquinone oxidoreductase, SQR, activity are markedly and equally downregulated when subunits SDHA and SDHB are targeted, and also when SDHC and SDHD are inhibited |
724698 |
| 1.3.5.1 | down |
Dhh1, a DEAD box protein, is required for the degradation of SDH4 mRNA in iron-deficient conditions. Furthermore, Cth2, an RNA-binding protein responsible for binding to AU-rich elements (ARE), promotes the 5' to 3' degradation of SDH4 mRNA. The final results suggest that Cth2 protein recruits the Dhh1 helicase to promote SDH4 mRNA decay in response to iron-deficiency |
698817 |
| 1.3.5.1 | down |
fnr and arcA gene products both act to repress SDHC expression in response to oxygen. The EIICBGlc protein (the ptsG gene product) is a crucial mediator of the repression of the sdhCDAB operon in the presence of glucose. It acts via the transcription factor crp, which directly regulates expression of the sdhCDAB operon. The glucose repression of this operon occurs in a cAMP-dependent manner |
762781 |
| 1.3.5.1 | down |
fumarate reductase expression is repressed under conditions of growth during which electron transport to oxygen or to nitrate is possible |
707291 |
| 1.3.5.1 | down |
in Neisseria meningitides low iron condition leads to high expression of NrrF. The latter is an sRNA that targets sdhCDAB transcript and promotes its degradation with the assistance of Hfq chaperone. The concentration of iron is sensed by Fur which represses the genes responsible for iron uptake with the assistance of ferrous iron as a corepressor |
762781 |
| 1.3.5.1 | down |
low levels of NFR-1 downregulate SDHA and thereby SDH complex expression. This stabilizes HIF-1 and promotes its nuclear translocation and high expression of glucose transporters and heme oxygenase-1. Deacetylation also occurs in histones by histone deacetylases (HDACs). The inhibition of class I HDACs results in higher expression of SDH and promotion of oxidative phosphorylation in skeletal muscles and adipose tissues. Chidamide, a histone deacetylase inhibitor increases SDHA expression |
762781 |
| 1.3.5.1 | up |
expression is upregulated in plants exposed to drought. The SDH1-like transcript level begins to increase when the leaf relative water content decreases to 78% and peaks when the relative water content drops to 57%. In stressed leaves sprayed with abscisic acid, SDH1 mRNA accumulates in greater levels compared to stressed leaves that do not receive abscisic acid. The enzymatic activity increases 1.5fold in the mature leaves of abscisic acid-treated plants |
743516 |
| 1.3.5.1 | up |
fumarate reductase is expressed under anaerobic growth conditions |
707291 |
