EC Number   |
Expression |
Reference |
|---|
    1.3.3.3 | down |
addition of NaHS suppresses enzyme promoter activity |
764113 |
| 1.3.3.3 | up |
cystathionine gamma-lyase deficient mice exhibit elevated enzyme expression in the liver |
764113 |
| 1.3.3.3 | up |
enzyme expression is induced by 5-fluorouracil |
764514 |
| 1.3.3.3 | up |
in subcutaneous A431 tumors in mice, pretreatment with vitamin D induces the expression of CCAAT-enhancer binding proteins (C/EBPbeta) isoforms, and of coproporphyrinogen oxidase (CPO). Vitamin D leads to strong accumulation of protoporphyrinogen-IX, PpIX. The murine CPO gene upstream region contains many competent C/EBP binding sites, analysis of C/EBPbeta and enzyme CPO interaction analysis, binding site analysis, overview. All C/EBP sites in murine CPO are asymmetric, with wide divergence between the two half-sites, fifteen functional C/EBP binding motifs in the mCPO promoter are found |
745755 |
| 1.3.3.3 | up |
pretreatment with vitamin D induces the expression of CCAAT-enhancer binding proteins (C/EBPbeta) isoforms, and of coproporphyrinogen oxidase (CPO). Vitamin D leads to strong accumulation of protoporphyrinogen-IX, PpIX. When MEL cells are incubated in 1% DMSO, large amounts of porphyrins are produced and under these conditions C/EBPbeta expression is upregulated. Concurrently, CPO expression is increased at both mRNA and protein levels, and higher levels of protoporphyrinogen-IX are generated in response to exogenously added 5-aminolevulic acid. LNCaP carcinoma lines respond to calcitriol with increases in enzyme CPO and protoporphyrinogen-IX levels concurrently. The human CPO gene upstream region contains many competent C/EBP binding sites, analysis of C/EBPbeta and enzyme CPO interaction analysis, binding site analysis, overview. Eighteen functional C/EBP binding motifs in the mCPO promoter are found, all are predicted to bind C/EBPs with moderate or higher affinity |
745755 |
