2.4.1.345 | GDP-alpha-D-mannopyranose + 1-acyl-3-(2-(6-O-acyl-alpha-D-mannopyranosyl)-1D-myo-inositolphospho)-2-acyl-sn-glycerol = GDP + 1-acyl-3-(2-(6-O-acyl-alpha-D-mannopyranosyl)-6-O-alpha-D-mannopyranosyl-1D-myo-inositolphospho)-2-acyl-sn-glycerol |
based on structural, calorimetric, and mutagenesis studies, a model is proposed wherein PimA attaches to the membrane through its N-terminal domain, and this association leads to enzyme activation |
680790 |