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Posttranslational Modification
Commentary
Reference
1.2.1.30
phosphopantetheinylation
posttranslational phosphopantetheinylation of a serine group in the recombinant CAR that is necessary for activity
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763297
1.2.1.30
side-chain modification
The phosphopantetheinyl-binding domain is recognized by a phosphopantetheinyl transferase enzyme, which attaches a phosphopantetheinyl residue to a conserved serine. Only upon this post-translational modification, the enzymes become active and are able to engage in the catalytic cycle
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763290
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