EC Number   |
Application |
Reference |
|---|
    1.1.1.86 | biofuel production |
engineering of Klebsiella pneumoniae to produce 2-butanol from crude glycerol as a sole carbon source by expressing acetolactate synthase (ilvIH), keto-acid reducto-isomerase (ilvC) and dihydroxyacid dehydratase (ilvD) from Klebsiella pneumoniae, and aalpha-ketoisovalerate decarboxylase (kivd) and alcohol dehydrogenase (adhA) from Lactococcus lactis. The engineered strain produces 2-butanol (160 mg/l) from crude glycerol. Elimination of the 2,3-butanediol pathway from the recombinant strain by inactivating alpha-acetolactate decarboxylase (adc) improves the yield of 2-butanol 320 mg/l |
-, 735831 |
| 1.1.1.86 | drug development |
the enzyme is a promising target for the design of herbicides |
698065, 699243 |
| 1.1.1.86 | drug development |
the enzyme is a target for herbicide drug development, computer-aided drug design |
697346 |
| 1.1.1.86 | industry |
Sac-KARI is one of the rare enzymes that displays high activity at elevated temperatures, a broad range of pH tolerance and is able to utilize both NADH and NADPH as cofactors. These properties make it a potential candidate for use in metabolic engineering or industrial applications under anaerobic or harsh conditions |
-, 763730 |
