EC Number |
Natural Substrates |
---|
2.4.1.80 | more |
enzyme decreases apoptosis and induces multidrug resistance, functional interaction with RTN-1C modulates enzyme activity and regulates chemotherapeutic-induced apoptosis in neuroepithelioma cells |
2.4.1.80 | more |
lipid profile of the parasite at different developmental stages, overview |
2.4.1.80 | more |
the enzyme has dual function as negative regulator of cell death mediated by proapoptotic factors and in catalyzing the formation of glucosylceramide, the core structure of major glycosphingolipids, ceramide generation might be a signal pathway |
2.4.1.80 | UDP-glucose + an N-acylsphingosine |
- |
2.4.1.80 | UDP-glucose + ceramide |
- |
2.4.1.80 | UDP-glucose + ceramide |
ceramide and its metabolites are important mediators of apoptosis and cell survival |
2.4.1.80 | UDP-glucose + ceramide |
key enzyme in the synthesis of major glycosphingolipids in vertebrates |
2.4.1.80 | UDP-glucose + N-acylsphingosine |
- |
2.4.1.80 | UDP-glucose + N-acylsphingosine |
regulation of intracellular ceramide is closely related to drug resistance and DOX-induced apoptosis |
2.4.1.80 | UDP-glucose + N-acylsphingosine |
enzyme is involved in renal growth, neuronal differentiation, the establishment of the water permeability barrier in keratinocytes, and multidrug resistance in cancer cell |