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EC Number
Natural Substrates
Commentary (Nat. Sub.)
1.1.1.176
12-ketochenodeoxycholic acid + NADH
-
1.1.1.176
12-oxolithocholic acid + NADH + H+
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1.1.1.176
12-oxolithocholic acid + NADPH + H+
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1.1.1.176
cholate + NAD+
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1.1.1.176
cholate + NADP+
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1.1.1.176
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multistep conversion of cholic acid into ursodeoxycholic acid. Enzyme sources are 7alpha-HSDH from Clostridium absonum (crude extract), 12alpha-HSDH from Clostridium group P, 7beta-HSDH from Clostridium absonum
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