EC Number   |
Localization |
GeneOntology No. |
Reference |
|---|
   2.3.1.297 | cell membrane |
- |
- |
754626 |
| 2.3.1.297 | endoplasmic reticulum |
- |
GO:0005783 AmiGO QuickGO |
-, 754083 |
| 2.3.1.297 | endoplasmic reticulum membrane |
Lac1p and Lag1p are integral membrane proteins with six to eight predicted transmembrane domains. Co-subunit Lip1 is also an integral membrane protein, with one transmembrane domain. Its short N-terminal part is cytoplasmic and not required for ceramide synthesis. Analysis of membrane topology of the heterotrimer for ceramide synthase catalytic activity, overview |
GO:0005789 AmiGO QuickGO |
-, 753414 |
| 2.3.1.297 | endoplasmic reticulum membrane |
transmembrane topology of topology of the Lag1p and Lac1p subunits in yeast using insertion of glycosylation sites and factor Xa-cleavage sites in the loops between the predicted transmembrane segments, method, overview. The N- and C-termini of the proteins are in the cytoplasm and eight putative membrane-spanning domains are identified in Lag1p and Lac1p. The conserved Lag motif, potentially containing the active site, is most likely embedded in the membrane |
GO:0005789 AmiGO QuickGO |
-, 752702 |
| 2.3.1.297 | membrane |
LASS3 has up to six transmembrane spanning domains |
GO:0016020 AmiGO QuickGO |
752701 |
| 2.3.1.297 | membrane |
liver microsomal membranes from CerS2 null mice display higher membrane fluidity and show morphological changes. Membrane morphology is studied by fluorescence microscopy, overview |
GO:0016020 AmiGO QuickGO |
754089 |
| 2.3.1.297 | microsome |
- |
- |
-, 752718, 752793, 752835, 753414, 754045, 754089, 754096 |
| 2.3.1.297 | mitochondrial membrane |
- |
GO:0031966 AmiGO QuickGO |
753223 |
