Cloned (Comment) | Organism |
---|---|
cloning of wild-type and construction of knock-out mutant, functional expression in Saccharomyces cerevisiae strain 334, expression of wild-type leads to accumulation of beta-D-glucopyranosyl ceramides, absent in wild-type Saccharomyces cerevisiae, knock-out mutation is not lethal | Candida albicans |
functional expression in Saccharomyces cerevisiae strain 334 | Komagataella pastoris |
functional expression of 1 isozyme in Saccharomyces cerevisiae strain 334 | Caenorhabditis elegans |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
UDP-glucose + N-acylsphingosine | Komagataella pastoris | - |
UDP + D-glucosyl-N-acylsphingosine | - |
? | |
UDP-glucose + N-acylsphingosine | Caenorhabditis elegans | - |
UDP + D-glucosyl-N-acylsphingosine | - |
? | |
UDP-glucose + N-acylsphingosine | Candida albicans | - |
UDP + D-glucosyl-N-acylsphingosine | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Caenorhabditis elegans | - |
several isoforms | - |
Candida albicans | - |
- |
- |
Komagataella pastoris | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
UDP-glucose + N-acylsphingosine | - |
Komagataella pastoris | UDP + D-glucosyl-N-acylsphingosine | - |
? | |
UDP-glucose + N-acylsphingosine | - |
Caenorhabditis elegans | UDP + D-glucosyl-N-acylsphingosine | - |
? | |
UDP-glucose + N-acylsphingosine | - |
Candida albicans | UDP + D-glucosyl-N-acylsphingosine | - |
? | |
UDP-glucose + N-acylsphingosine | i.e. ceramide | Komagataella pastoris | UDP + D-glucosyl-N-acylsphingosine | i.e. glucosylceramide | ? | |
UDP-glucose + N-acylsphingosine | i.e. ceramide | Caenorhabditis elegans | UDP + D-glucosyl-N-acylsphingosine | i.e. glucosylceramide | ? | |
UDP-glucose + N-acylsphingosine | i.e. ceramide | Candida albicans | UDP + D-glucosyl-N-acylsphingosine | i.e. glucosylceramide | ? |
Synonyms | Comment | Organism |
---|---|---|
GlcCer synthase | - |
Komagataella pastoris |
GlcCer synthase | - |
Caenorhabditis elegans |
GlcCer synthase | - |
Candida albicans |