Organism | UniProt | Comment | Textmining |
---|---|---|---|
Drosophila melanogaster | - |
- |
- |
Synonyms | Comment | Organism |
---|---|---|
AGBE | - |
Drosophila melanogaster |
glycogen branching enzyme | - |
Drosophila melanogaster |
General Information | Comment | Organism |
---|---|---|
malfunction | enzyme mutations cause porphyria | Drosophila melanogaster |
physiological function | the enzyme is a regulator of iron homeostasis. The enzyme interacts physically with the holoform of iron regulatory protein 1A (IRP1A) and Cisd2, an ortholog of vertebrate mitoNEET. This synergistic interaction ensures that holo-IRP1A remains functional | Drosophila melanogaster |