Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | P21980 | - |
- |
Mammalia | - |
8 distinct transglutaminase isoenzymes have been identified on the genomic level, 6 have been isolated and characterized: factor XIII, type 1 or keratinocyte transglutaminase, type 2 or tissue transglutaminase, type 3 or epidermal transglutaminase, type 4 or prostate transglutaminase and type 5 transglutaminase | - |
Rattus norvegicus | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
protein-bound gamma-glutamine + alkylamine | - |
Rattus norvegicus | protein N5-alkylglutamine + NH3 | - |
? | |
protein-bound gamma-glutamine + alkylamine | - |
Homo sapiens | protein N5-alkylglutamine + NH3 | - |
? | |
protein-bound gamma-glutamine + alkylamine | endogenous substrates: cellular proteins e.g. aldolase, glyceraldehyde-3-phosphate dehydrogenase, phosphorylase kinase, crystallins, gluthathione S-transferase, actin, myosin, troponin, beta-tubulin, tau, Rho A, histone, alpha-oxoglutarate dehydrogenase, cytochromes, erythrocyte band III, CD38, acetylcholine esterase, collagen, fibronectin, fibrinogen, vitronectin, osteopontin, nidogen, laminin, LTBP-1, osteonectin, osteocalcin, substance P, phospholipase A2, midkine, exogenous substrates: wheat gliadin, whey proteins, soy proteins, pea legumin, Candida albicans surface proteins, HIV envelope glycoproteins gp120 and gp41, HIV aspartyl proteinase, hepatitis C virus core protein | Mammalia | protein N5-alkylglutamine + NH3 | - |
? |