Inhibitors | Comment | Organism | Structure |
---|---|---|---|
3-(3,4-dihydroxyphenyl)-N-methylpropanamide | potent inhibitor, completely inactive in the cell-based assay | Pseudomonas aeruginosa | |
benzyl 3-(3,4-dihydroxyphenyl)propanoate | - |
Pseudomonas aeruginosa | |
methyl 3-(3,4-dihydroxyphenyl)propanoate | potent inhibitor | Pseudomonas aeruginosa | |
additional information | evaluation of selected substrates of the Medicago sativa chalcone synthase CHS2 as potential inhibitors of PqsD. Catechol derivatives possessing an ester moiety are able to reduce the production of 2-heptyl-4(1H)-quinolone in the bacterial cultures without affecting cellular growth | Pseudomonas aeruginosa |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Pseudomonas aeruginosa | P20582 | - |
- |
IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|
0.0059 | - |
pH not specified in the publication, temperature not specified in the publication | Pseudomonas aeruginosa | benzyl 3-(3,4-dihydroxyphenyl)propanoate | |
0.02 | - |
pH not specified in the publication, temperature not specified in the publication | Pseudomonas aeruginosa | methyl 3-(3,4-dihydroxyphenyl)propanoate | |
0.023 | - |
pH not specified in the publication, temperature not specified in the publication | Pseudomonas aeruginosa | 3-(3,4-dihydroxyphenyl)-N-methylpropanamide |