Literature summary for 2.1.1.356 extracted from

Gu, X.; Xu, T.; He, Y.
A histone H3 lysine-27 methyltransferase complex represses lateral root formation in Arabidopsis thaliana (2014), Mol. Plant, 7, 977-988.

Search for more literature for 2.1.1.356

Organism

Organism	UniProt	Comment	Textmining
Arabidopsis thaliana	P93831	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
root	-	Arabidopsis thaliana	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
S-adenosyl-L-methionine + histone H3(K27)	-	Arabidopsis thaliana	S-adenosyl-L-homocysteine + N-methylated histone H3(K27)	-	?

Synonyms

Synonyms	Comment	Organism
CLF	-	Arabidopsis thaliana

General Information

General Information	Comment	Organism
physiological function	a PRC2 (for Polycomb repressive complex 2) histone H3 lysine-27 (H3K27) methyltransferase complex functions to inhibit founder cell establishment during lateral root initiation. Functional loss of the PRC2 subunits EMF2 (for EMBRYONIC FLOWER 2) or CLF (for CURLY LEAF) leads to a great increase in the number of LRs formed in the primary root. The CLF H3K27 methyltransferase binds to chromatin of the auxin efflux carrier gene PIN FORMED 1 (PIN1), deposits the repressive mark H3K27me3 to repress its expression, and functions to down-regulate auxin maxima in root tissues and inhibit founder cell establishment	Arabidopsis thaliana

Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.

Release 2023.1 (January 2023)