Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
L-phenylalanine + H2O + O2 | Homo sapiens | primary amino acid catabolized by IL4I1 | phenylpyruvate + NH3 + H2O2 | - |
? | |
L-tryptophan + H2O + O2 | Homo sapiens | - |
3-(1H-indol-3-yl)-2-oxopropanoate + NH3 + H2O2 | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
dendritic cell | - |
Homo sapiens | - |
macrophage | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
L-phenylalanine + H2O + O2 | primary amino acid catabolized by IL4I1 | Homo sapiens | phenylpyruvate + NH3 + H2O2 | - |
? | |
L-tryptophan + H2O + O2 | - |
Homo sapiens | 3-(1H-indol-3-yl)-2-oxopropanoate + NH3 + H2O2 | - |
? |
Synonyms | Comment | Organism |
---|---|---|
IL4I1 | - |
Homo sapiens |
IL4I1 | interleukin 4 induced gene 1 | Homo sapiens |
L-amino acid oxidase | - |
Homo sapiens |
LAAO | - |
Homo sapiens |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
FAD | - |
Homo sapiens |
General Information | Comment | Organism |
---|---|---|
physiological function | IL41I inhibits bacterial growth. The antibiotic action of IL4I1 is mainly due to H2O2 and NH3 production whereas its L-amino acid oxidase activity does not sufficiently deplete the medium of Phe or Trp to inhibit bacterial growth | Homo sapiens |